DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and plcd3b

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_005156186.1	Gene:	plcd3b / 562569	ZFINID:	ZDB-GENE-081222-2	Length:	769	Species:	Danio rerio

Alignment Length:	304	Identity:	55/304 - (18%)
Similarity:	93/304 - (30%)	Gaps:	125/304 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 SLSAVCEAT-------------GADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDI------ 277
            ||...|:.|             ...|:.:.:...||:.|.....||.:...|....:::
Zfish   120 SLDVQCDTTEEAQHWVHGIRTLQGRVNNMTQKEKLDNWIYGYLKQADINHDGKMSYEEVQVLFKL 184

  Fly   278 ----LNLIY-----------------------IC-ENLNLPEVAAYWQQ---------VIDMNEY 305
                ||..|                       .| |.|..||:.|.:||         .:|:.|:
Zfish   185 VNIDLNEEYAASLFKKSDKSADGRLEHEEIELFCRELLRRPELDAVFQQYSANGCVLSTVDLREF 249

  Fly   306 QKRRFSQKIIESLFNTVSDKRIAILGFAF----KKNTGDTRETAAITVCQTLLEEGAAL------ 360
            .|.:...       :|:...:..||.:..    :||             |.:...|..:
Zfish   250 LKDQGED-------HTLVHAQSLILTYELNEWAQKN-------------QFMTANGFTMYMLSKE 294

  Fly   361 -DIYDPKVEPEQIIDDLTHP----SVTESPEKVKKAVQIHSD----PYSAVRATHALVICTEWDE 416
             |:|:|  :..::..|::||    .::.|........|:.||    ||  :||......|.|.|
Zfish   295 NDVYNP--DHRRVYQDMSHPLSHYFISSSHNTYLTKDQLISDSSVHPY--IRALSQGCRCVELD- 354

  Fly   417 FVDLDFKRIYQSMMKPAYIFDGRKILDHERLQQIGFHVQTIGKK 460
                              .:||.|       :.:.:|..|:..|
Zfish   355 ------------------CWDGEK-------EPVIYHGHTLTSK 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	54/301 (18%)
plcd3b	XP_005156186.1	PH-like	34..152	CDD:302622	5/31 (16%)
		EF-hand_7	163..215	CDD:290234	6/51 (12%)
		EF-hand_10	172..221	CDD:291454	4/48 (8%)
		EF-hand_like	226..306	CDD:286375	17/101 (17%)
		PLN02952	230..737	CDD:178538	35/194 (18%)
		PI-PLCc_GDPD_SF	306..592	CDD:301322	20/96 (21%)
		C2_PLC_like	624..752	CDD:175974
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000