DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and norpA

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001014720.1	Gene:	norpA / 31376	FlyBaseID:	FBgn0262738	Length:	1095	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	89/466 - (19%)
Similarity:	167/466 - (35%)	Gaps:	134/466 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SSERIAQWNSDKL----PIYEPGLDEVVKK--CRNVNLFFSTDIETAIKEADLIFISVNTPTKTC 92
            |:..:..|.|..:    ||...|.|:.::|  ..|::.|..:.....:|::.:.|::.|....:.
  Fly   542 STTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSR 606

  Fly    93 GNGKGRAADLK------YVESAARMIAEIAQSNKIVV-------------------------EKS 126
            ...||..||..      :..:..:|::...||:.:.:                         :|.
  Fly   607 IYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKD 671

  Fly   127 TVP--------VRAAESIMHILR----ANQKPG--IHYDILSNP------EF---LAEGTAINDL 168
            ..|        |.||:..:.::.    :::|.|  :..|:...|      ||   |.....:|.:
  Fly   672 FDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPV 736

  Fly   169 LNADRVLIGGEETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSL 233
            .|.|..:......|:  .||.:.. :||                |..|:     |.|||..::.|
  Fly   737 YNEDPFVFRKVVLPD--LAVLRFG-VYE----------------ESGKI-----LGQRILPLDGL 777

  Fly   234 SA----VCEATGAD--VSEVARAVGLDSRI----GSKFLQASV----GFGGSCFQK-DILNLIYI 283
            .|    |...|.|:  :|.....|.::.:|    |.:...|.:    ||.|:..|: :.:..:.|
  Fly   778 QAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGI 842

  Fly   284 CENLNLPEVAAYWQQVIDMNEYQKRR----FSQKIIESL-----FNTVSDKRIAILGFAFKKNTG 339
            .|     :.....:......|.:|:.    |....:|||     |..|..|:|..|....||:
  Fly   843 EE-----QSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKH-- 900

  Fly   340 DTRETAAITVCQTLLEEGAALDIYDPKVEPEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRA 404
             .:|..::...|     .||:|    |:...:..||:.:.:      .:|.::...:..::.:.|
  Fly   901 -AKERTSVQKTQ-----NAAID----KLIKGKSKDDIRNDA------NIKNSINDQTKQWTDMIA 949

  Fly   405 THALVICTEWD 415
            .|..   .|||
  Fly   950 RHRK---EEWD 957

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	89/466 (19%)
norpA	NP_001014720.1	PH_PLC_beta	17..149	CDD:270167
		PLN02952	224..786	CDD:178538	49/267 (18%)
		EF-hand_like	227..318	CDD:286375
		PI-PLCc_beta	318..653	CDD:176533	20/110 (18%)
		C2_PLC_like	689..806	CDD:175974	28/140 (20%)
		DUF1154	866..908	CDD:284131	12/44 (27%)
		Mer2	<887..1003	CDD:286200	19/92 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000