DRSC/TRiP Functional Genomics Resources

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Protein Alignment sgl and Plch1

DIOPT Version :9

Sequence 1:NP_476980.1 Gene:sgl / 38760 FlyBaseID:FBgn0261445 Length:476 Species:Drosophila melanogaster
Sequence 2:XP_017446352.2 Gene:Plch1 / 310463 RGDID:1561991 Length:1703 Species:Rattus norvegicus


Alignment Length:368 Identity:71/368 - (19%)
Similarity:122/368 - (33%) Gaps:119/368 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 ISVNTPTKTCGNGKGRAADLKYVESAARMIAEIAQSNKIVVEKSTVPV----------RAAESI- 136
            ::::..||...:..|...|.|..|.|...:...:..::.|:.:|::.|          |||.|. 
  Rat  1099 LALDPATKGLQDLHGMRTDEKEQERAKGFVGRKSTQSESVLSQSSLEVENLEGSKAKGRAATSFS 1163

  Fly   137 ---MHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGGEETPEGHQAVEKLSWIYEHW 198
               :..| .:..|.:|      ...:.:.|.|:||:| |..|....|:   ..::..|...:|..
  Rat  1164 LSDVSAL-CSDIPDLH------STAILQDTEISDLIN-DVTLTNANES---GSSISALIGQFEES 1217

  Fly   199 IPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCEATGADVSEVARAVGLDSRIGSKFLQ 263
            ..:.|:..                    :|.:.|.|...|.....|     |:||.:.|.:.|.|
  Rat  1218 NHRANVAV--------------------VSRLLSTSGTSEGVALPV-----ALGLQTPIKNGFSQ 1257

  Fly   264 ----ASVGFGGSCFQKDILNLIYICEN--LNLPEVAAYWQQVIDMNEYQKRRFSQKIIESLFNTV 322
                ||                ::|.:  ||.|..|.                :.|:..   |||
  Rat  1258 GKHKAS----------------FLCSSPELNKPSSAE----------------TTKLAN---NTV 1287

  Fly   323 SDKRIAILG--FAFKKNTGDTRETAAITVCQTLLEEGAALDIYDPKVEPEQIIDDLTHPSVTESP 385
            :   ..::|  .:..|...|..:.|...|.:..|.:       .|...|.|.         .:||
  Rat  1288 A---CGVIGSPISTPKPGDDASDKAKTRVTEDNLPD-------SPDAFPGQF---------PQSP 1333

  Fly   386 EKVKKAVQIHSDPYSAV-------RATHALVICTEWDEFVDLD 421
            ...:...|:.|.|..::       .|..||.|.:|....|::|
  Rat  1334 THGEDHRQVMSSPALSMPLAMEDTTADPALCINSEESSLVEID 1376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sglNP_476980.1 PLN02353 1..459 CDD:177986 71/368 (19%)
Plch1XP_017446352.2 PH-like 34..140 CDD:418428
EFh_PI-PLCeta1 158..298 CDD:320050
EF-hand motif 158..187 CDD:320050
EF-hand motif 194..223 CDD:320050
EF-hand motif 228..256 CDD:320050
EF-hand motif 265..298 CDD:320050
PI-PLCc_eta1 310..714 CDD:176569
C2_PLC_like 744..868 CDD:175974
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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