DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and Plcl2

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_038939092.1	Gene:	Plcl2 / 301173	RGDID:	1305941	Length:	1128	Species:	Rattus norvegicus

Alignment Length:	165	Identity:	32/165 - (19%)
Similarity:	67/165 - (40%)	Gaps:	18/165 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 AINDLLNADRVLIGGEETP-----EGHQAVEKLSWIYEHW--IPKQNILTTNTWSSELSKLAANA 221
            ::.|::|  :......|.|     |.|.::::...:.:|.  |....:.||:....|....:.:.
  Rat   499 SVIDIIN--KYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDV 561

  Fly   222 FLAQRISSINSLSAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQ--KDILNLIYIC 284
            ...:.:.....||:.|.....||::......:..|:|.:.::.........||  ||:..|:.||
  Rat   562 LKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKDLSELVSIC 626

  Fly   285 ENLNLPE------VAAYWQQVIDMNEYQKRRFSQK 313
            :::...|      |..|| :|...||....:::.:
  Rat   627 KSVQFKEFQVSFQVQKYW-EVCSFNEVLASKYANE 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	32/165 (19%)
Plcl2	XP_038939092.1	PH_PLC_eta	144..252	CDD:270170
		EFh_PRIP2	272..415	CDD:320053
		EF-hand motif	272..301	CDD:320053
		EF-hand motif	308..339	CDD:320053
		EF-hand motif	344..372	CDD:320053
		EF-hand motif	381..414	CDD:320053
		PI-PLCc_PRIP_metazoa	426..722	CDD:176539	32/165 (19%)
		C2_PLC_like	754..882	CDD:175974
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000