DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and Plcb1

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001071109.1	Gene:	Plcb1 / 24654	RGDID:	3344	Length:	1216	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	44/174 - (25%)
Similarity:	65/174 - (37%)	Gaps:	42/174 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 YIC------ENLNLPEVAAYWQQVIDMNEYQKRRFSQKIIESLFNTV--------SDKRIAILGF 332
            |||      :.|.||.|..|    |::.:|....::. :||:|.|.:        ..|::|.|..
  Rat   773 YICLRNERNQPLMLPAVFVY----IEVKDYVPDTYAD-VIEALSNPIRYVNLMEQRAKQLAALTL 832

  Fly   333 ----AFKK--NTGDTRETAAITVCQTLLEEG----AALDIYDPKVEPEQIIDDLTHPSVTESPEK 387
                ..||  :.|:|...|......|..|.|    |.|   .|| .|.|.......|...::|.|
  Rat   833 EDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTATL---APK-PPSQAPHSQPAPGSVKAPAK 893

  Fly   388 VKKAVQIHSDPYSAVRATHALVI--CTEWDEFVDLDFKRIYQSM 429
            .:..:|      |.:....|..|  ..:...||.|. |:.|:.|
  Rat   894 TEDLIQ------SVLTEVEAQTIEELKQQKSFVKLQ-KKHYKEM 930

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	44/174 (25%)
Plcb1	NP_001071109.1	PH_PLC_beta	22..148	CDD:270167
		PLN02952	216..784	CDD:178538	3/10 (30%)
		EF-hand_like	224..314	CDD:286375
		PI-PLCc_beta	316..643	CDD:176533
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	469..534
		C2_PLC_like	677..796	CDD:175974	9/26 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	834..891		15/60 (25%)
		DUF1154	903..939	CDD:284131	8/29 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	967..989
		PLC-beta_C	1003..1172	CDD:285865
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1072..1095
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1172..1216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000