Protein Alignment sgl and Plcg2

DIOPT Version :9

• Sequence 1: NP_476980.1
• Gene: sgl / 38760
• FlyBaseID: FBgn0261445
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_758489.1
• Gene: Plcg2 / 234779
• MGIID: 97616
• Length: 1265
• Species: Mus musculus
• Alignment Length: 492
• Identity: 84/492 - (17%)
• Similarity: 159/492 - (32%)
• Gaps: 168/492 - (34%)

  Fly    42 NSDKLPIYEPGLDEVVKKCRNVNLFFSTDIETAIKEADLIFISVNTPTKTCGNGKGRAADLKYVE 106
            |.|.||.||                     ::.||.|    :.:.| ..|..|.:....:.:.|:
Mouse     6 NVDTLPEYE---------------------KSQIKRA----LELGT-VMTVFNARKSTPERRTVQ 44

  Fly   107 --SAARMIAEIAQSNKI-----VVE-------KSTVPVRAAESIMHILRANQKPGIHYDILSNPE 157
              ...|.:|....::||     ::|       |::.....|:::.|      |....:.||...:
Mouse    45 MIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRH------KAECCFTILYGTQ 103

  Fly   158 FLAEGTAINDLLNADRVLIGGEETPEGHQAVEKLSWI---------------YEHWIPKQNILTT 207
            |:....::              .|.....||:.||.:               .|.|:.||.....
Mouse   104 FVLSTLSL--------------ATDSKEDAVKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVD 154

  Fly   208 NTWSSELSKLAANAFLAQ---RISSINSLSAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFG 269
            .|..:.:|.......|..   ::|.|..|.......||...|::            |.|..:.:.
Mouse   155 QTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELS------------FEQFHLFYK 207

  Fly   270 GSCF--QKDIL------NLIYICENLNLPEVAA----------------YWQQVIDMNEYQKRRF 310
            ...|  ||.||      :.::|..|.:.|:.:|                .|.|  |:|:.::|
Mouse   208 KLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQ--DLNKVRER-- 268

  Fly   311 SQKIIESLFNTVSDKRIAI---LGFAFKKNTGDTRETAAITVCQTLLEEGAALDIYDPK---VEP 369
            ..|.|:......::..:.:   |.:.|      :||.:                |:|.|   |:.
Mouse   269 MTKFIDDTMRETAEPFLFVDEFLTYLF------SRENS----------------IWDEKYDAVDM 311

  Fly   370 EQIIDDLTHPSVTESPEKVKKAVQIHSDPYSA--VRATHALVICTE----------------WDE 416
            :.:.:.|:|..::.|........|:.|:..:.  :|...|...|.|                |..
Mouse   312 QDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTR 376

  Fly   417 FVDLDFKRIYQSMMKPAYIFDGRKIL----DHERLQQ 449
            ...:.|..:.|::...|::.....::    :|..::|
Mouse   377 TTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQ 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	84/492 (17%)
Plcg2	NP_758489.1	PH_PLC_gamma	22..140	CDD:270168	21/138 (15%)
		PH-like	235..>276	CDD:302622	9/44 (20%)
		PI-PLCc_gamma	311..>458	CDD:176534	15/103 (15%)
		PH-like	475..>512	CDD:302622
		SH2_N-SH2_PLC_gamma_like	527..627	CDD:199829
		SH2_C-SH2_PLC_gamma_like	641..744	CDD:198186
		SH3_PLCgamma2	773..827	CDD:212902
		PHsplit_PLC_gamma	<840..909	CDD:270054
		PI-PLCc_GDPD_SF	<926..1031	CDD:301322
		C2_PLC_like	1061..1187	CDD:175974

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000