Protein Alignment sgl and egl-8

DIOPT Version :9

• Sequence 1: NP_476980.1
• Gene: sgl / 38760
• FlyBaseID: FBgn0261445
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001300014.1
• Gene: egl-8 / 178537
• WormBaseID: WBGene00001177
• Length: 1512
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 100/551 - (18%)
• Similarity: 185/551 - (33%)
• Gaps: 161/551 - (29%)

  Fly     7 GAGYV-----------------GGPTCAVMALKCPDIVITLVDKSSERIAQWNSD-KLPIYEP-- 51
            |:||:                 ..|...|:|..|...||:         .|:.|| |:..|..
 Worm   944 GSGYLLKPDFLRRPDRTFDPFSESPVDGVIAAHCSVRVIS---------GQFLSDRKIGTYVEVE 999

  Fly    52 --GL-DEVVKKCRNVNLFFSTDIETAIKEADLIFISVNTPTKTC-------GNGK---GRAADLK 103
              || .:.::|.....:.....:.....|...:|..|..|....       .|||   .|...|.
 Worm  1000 MYGLPTDTIRKEHKTKVIPGNGLNPVYNEDPFVFRKVVLPELAVLRFAVYDENGKQLGQRILPLD 1064

  Fly   104 YVESAARMIAEIAQSNKIVVEKSTVPVRAAESIMHILRANQKPGIHYDILSNPE-FLAE------ 161
            .:::..|.|:..:.:|:..:   ..||...:.::.....::..|: .|.|::|. ||:|
 Worm  1065 GLQAGYRHISLRSDTNQSFI---LSPVLFVQIVIKTYVPDELSGL-VDALADPRAFLSEQKKRQE 1125

  Fly   162 --------GTAINDLLNADRVLIGGEETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSELSKLA 218
                    .:.|.|:.|...:.:...:.|                 |:||       .|....||
 Worm  1126 ALAHMGVDDSDIPDVPNTRNMALRHVKQP-----------------PRQN-------GSSADLLA 1166

  Fly   219 ANAFLAQRISSINSLSAVCEATGADVSEVARAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIYI 283
            .|.....  :..:..|::..:|....:|..:.|.:|.                 |:.|.:.:..:
 Worm  1167 NNGQTGS--ARGDQTSSMASSTIRSPNEQPQPVAVDK-----------------FKVDPIEVDDL 1212

  Fly   284 CENLNLPEVAAYWQQVID--MNEYQKRRFS-------QKIIESL--FNTVSDKRIAILGFAFKKN 337
            ..:....::...:|:.:|  ..::||:|.|       ::...|:  ..|..||.|.....:.||.
 Worm  1213 RRDKAFAKLLKRFQKELDDLRKKHQKQRDSIQKQQPARRRNSSIAWIQTNVDKLITNNRRSTKKE 1277

  Fly   338 TGDTRE--------------TAAITVCQTLLEEGAALDIYD---PKVEPEQIIDDLTHPSVTESP 385
            .|..|.              |..::||.   ..||:...|.   |........|....|:...||
 Worm  1278 KGSRRSLTASVSSGCGSASGTVTVSVCS---PSGASCSGYSTGGPSTPVACNSDGTGSPATIGSP 1339

  Fly   386 --------EKVKKAVQIHSDPYSAVRATHALVICTEWDEFVDLDFKRIYQSMMKPAYIFD-GRKI 441
                    ::|:..|...:..:||:...|      :.:||   :.|::   .:|..  || .||:
 Worm  1340 VPQDLVNNDRVRSLVNTQTGEWSAMVRRH------DEEEF---ELKKV---QLKEQ--FDLLRKL 1390

  Fly   442 LDHERLQQ---IGFHVQTIGKKYQRTGLLRS 469
            :...:..|   :...::..||..::|...:|
 Worm  1391 MSEAQKNQMLALKLRLEAEGKDLKQTQTKKS 1421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	96/539 (18%)
egl-8	NP_001300014.1	PH_PLC_beta	17..142	CDD:270167
		EF-hand_like	249..339	CDD:286375
		PI-PLCc_beta	339..>495	CDD:176533
		PI-PLCc_GDPD_SF	<839..942	CDD:301322
		C2_PLC_like	976..1096	CDD:175974	25/131 (19%)
		DUF1154	1202..1244	CDD:284131	8/41 (20%)
		PLC-beta_C	1370..1511	CDD:285865	13/60 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000