DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and plcb2

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_017952419.2	Gene:	plcb2 / 101734935	XenbaseID:	XB-GENE-6045997	Length:	1250	Species:	Xenopus tropicalis

Alignment Length:	267	Identity:	48/267 - (17%)
Similarity:	88/267 - (32%)	Gaps:	95/267 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 NAFLAQRISSINSLSAVCEATGADVSEVA--RAVGLDSRIGSKFLQASVGFGGSCFQKDILNLIY 282
            |.|||:.::.:         ||.|:.::.  ..|.....:            |..:..|||:::
Frog    92 NNFLAKALTIV---------TGPDMVDLTFHNFVSYKENV------------GKAWAADILSVV- 134

  Fly   283 ICENLNLPEVAAYWQQVIDMNEYQKRRFSQKI-IESLFNTVSDKRIAILGFAFKKNTGD-TRETA 345
              .|..:|....|             .|.:|| ::......|:.:|.:..| |:....| .|...
Frog   135 --TNPLVPNACRY-------------SFFEKIHVKLQLQLNSEGKIPVRNF-FQMFPADRKRVEQ 183

  Fly   346 AITVCQTLLEEGAALDIYDPKVEPEQI-------------IDDL-------THPSVTE------- 383
            |:..|.  |.:|.. |..:|:..||.:             ||::       ..|.:|:
Frog   184 ALNSCH--LSKGKN-DAINPEDFPESVFRTFLMQLCPRPEIDEIFTSYHSKAKPYMTKVHLTKFI 245

  Fly   384 -----------------SPEKVKKAVQIHSDPYSAVR----ATHALV--ICTEWDEFVDLDFKRI 425
                             ..|:|:..::.:......|:    :...:|  :|...:....||...|
Frog   246 NQKQRDSRLNELIFPPAKTEQVQGLIEKYEPSVINVQRGQLSPEGMVWFLCGSENSITSLDKIPI 310

  Fly   426 YQSMMKP 432
            ||.|.:|
Frog   311 YQDMSQP 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	48/267 (18%)
plcb2	XP_017952419.2	PH_14	12..141	CDD:407659	13/72 (18%)
		EFh_PI-PLCbeta2	149..299	CDD:320039	25/153 (16%)
		PI-PLCc_beta2	311..641	CDD:176561	4/7 (57%)
		C2_PLC_like	675..794	CDD:175974
		DUF1154	872..908	CDD:399553
		PLC-beta_C	956..1131	CDD:400858
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000