DRSC/TRiP Functional Genomics Resources

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Protein Alignment sgl and plcg2

DIOPT Version :9

Sequence 1:NP_476980.1 Gene:sgl / 38760 FlyBaseID:FBgn0261445 Length:476 Species:Drosophila melanogaster
Sequence 2:XP_017949009.1 Gene:plcg2 / 100496686 XenbaseID:XB-GENE-952431 Length:1260 Species:Xenopus tropicalis


Alignment Length:371 Identity:62/371 - (16%)
Similarity:119/371 - (32%) Gaps:112/371 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   194 IYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSINSLSAVCEATGADVSEVARAVGLDSRIG 258
            |.|.|:.||......|..:.:|.......|:|.....||:..        :.:....:|: .|..
 Frog   143 IIESWLRKQIYSVDQTRKNSISFRELKTILSQANFKANSMRV--------LKDKLTEIGI-QRDD 198

  Fly   259 SKFLQASVGFGGSCF--QKDIL------NLIYICENLNLPEVAAY----WQQVI----------D 301
            ..|....|.:....|  ||.||      :.::|..|::.|:.:|.    :|:.:          |
 Frog   199 ISFEHFHVFYKKLMFEQQKMILDEFRKDSSVFILGNVDRPDGSAVHLHDFQRFLVHEQQESPAQD 263

  Fly   302 MNEYQKRR----------------FSQKIIESLF---NTVSDKRIAILGFAFKKN---------- 337
            :::.::|.                |..:.:..||   |::.|::...:......|          
 Frog   264 LSKVRERMTKFVDDTMRETAEPFLFVDEFLTYLFSKENSIWDEKYDTISVQNMNNPLSHYWIASS 328

  Fly   338 -----TGD----TRETAAITVCQTLLEEGAALDIYD---------------PKVEPEQIIDDLTH 378
                 |||    ...|.|...|..:......||.:|               .|::.:.::..:..
 Frog   329 HNTYLTGDQLRSESSTEAYVRCLRMGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRD 393

  Fly   379 PSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWDEFVDLDFKRIYQSMM--KPAYI------ 435
            .:...|...|..:::.|              .|.|....:...||.:...::  ||...      
 Frog   394 HAFATSEYPVILSIEEH--------------CCVEQQRHMAKVFKEVLGELLLTKPIEATADQLP 444

  Fly   436 ----FDGRKILDHERLQ--QIGFHVQTIGKKYQRTGLLRSWGIVPQ 475
                ..||.|:.|::|:  ..|.:.:...::....|.|..|..:.|
 Frog   445 SPTQLKGRIIIKHKKLETKNPGTNTENHKEEQNLQGELYMWDGIDQ 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sglNP_476980.1 PLN02353 1..459 CDD:177986 58/353 (16%)
plcg2XP_017949009.1 PH_PLC_gamma 24..141 CDD:270168
EFh_PI-PLCgamma2 147..300 CDD:320045 28/161 (17%)
PI-PLCc_gamma 313..>460 CDD:176534 24/160 (15%)
PH-like 479..>511 CDD:388408 4/12 (33%)
SH2_N-SH2_PLC_gamma_like 526..627 CDD:199829
SH2_C-SH2_PLC_gamma_like 641..744 CDD:198186
SH3_PLCgamma2 774..828 CDD:212902
PH-like <841..910 CDD:388408
PI-PLCc_GDPD_SF <917..1032 CDD:387364
C2_PLC_like 1060..1186 CDD:175974
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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