DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and plch2

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_031761350.1	Gene:	plch2 / 100487353	XenbaseID:	XB-GENE-988591	Length:	1578	Species:	Xenopus tropicalis

Alignment Length:	514	Identity:	97/514 - (18%)
Similarity:	171/514 - (33%)	Gaps:	173/514 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PDIVITLVDKSSE---RIAQWNSDKLPIYE-------PGL-----------DEVVKKCRNVNLFF 67
            |:|.|...:.||:   ...:.:...||.:|       |.|           .:.:|..|.::::.
Frog   965 PEIAIDSKENSSDGPSEDRETDDSSLPRFEKDPESASPALPSRDGTNVELNSKGLKDPRQLSIYR 1029

  Fly    68 ST----DIETAIKEADLIFISVNTPTK----TCGNGKGRAADLKYVESAARMIA------EIAQS 118
            |.    .:|| |||..| |......|.    .|.......|..:|.||.:...:      .:.:.
Frog  1030 SASSLCSLET-IKEEPL-FAKEKPSTSPQPVACFTSCESTACDQYKESQSECSSPAITSENVQRP 1092

  Fly   119 NKIVVEKSTVPVRAAESIMHILRANQKPGIHYDILSNPEFLAEGTAINDLLNADRVLIGGEETPE 183
            :|:.||.:.:.|.|..:.:|.......||..|:. .|.:.|:..:..:|..|    ||.......
Frog  1093 SKLNVEPAIIKVLAISNGLHPHNGKLNPGKAYND-RNGKVLSSVSGKSDCTN----LINSSLIKP 1152

  Fly   184 GHQAVEKLSW-IYEHWIPKQNILTTNTWSSELSKLAANAFLAQRISSIN---------------- 231
            |...:..:|. :.|.:..|.|      .:::.|..|:|..:|.||...|
Frog  1153 GLSLLADVSRNVNEQYQVKAN------QAAQSSIHASNTSVANRIMCTNLPDHQTSSKPNMKHLI 1211

  Fly   232 -------------------------------------------SLSAVCEATGADVSEVARAVGL 253
                                                       ||::.|:   :.|:||.....:
Frog  1212 VPPVQRSQYDRPDSKPSVVHAGKHTPVRRAKSEGYVVSDCSALSLNSTCQ---SPVAEVYSDATV 1273

  Fly   254 DSRIGSKF----LQASVGFGGSCFQKDILNLIYICENLNLPEVAAYWQQVIDMNEYQKRRFSQKI 314
            :.||.||.    .:.|:....|....|.:      .:|:||.:|.  :.::|::      .|...
Frog  1274 NDRIWSKLELNSHRDSMSSSSSKSSNDTV------IDLSLPNLAR--KSLLDLD------ISDDN 1324

  Fly   315 IES--LFNTVSDKRIAILGFAFKKNTGDTRETAAITVCQTLLEEGAALDIYDPK-VEPEQIIDDL 376
            .|:  |.||:..          :..|..|:|          :..|.:....:|. |...|.||:|
Frog  1325 FENIHLNNTIRP----------RSATSSTKE----------MSLGVSKSKSNPNLVSNNQAIDEL 1369

  Fly   377 THPSVTESPEKVKKAVQIHSDPYSAVRATHALVICTEWDE-FVDLDFKRIYQSMMKPAY 434
            :...:..||.:..        |:...|.|        |:. :||    .:.|:..||::
Frog  1370 SSRPLARSPTEAL--------PHLPRRNT--------WNRLYVD----SLKQANKKPSF 1408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	97/514 (19%)
plch2	XP_031761350.1	PH_PLC_eta	44..150	CDD:270170
		EFh_PI-PLCeta2	168..308	CDD:320051
		PI-PLCc_GDPD_SF	320..747	CDD:417475
		C2_PLC_like	777..901	CDD:175974
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000