DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgl and LOC100149080

DIOPT Version :9

Sequence 1:	NP_476980.1	Gene:	sgl / 38760	FlyBaseID:	FBgn0261445	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_021324223.1	Gene:	LOC100149080 / 100149080	-ID:	-	Length:	918	Species:	Danio rerio

Alignment Length:	432	Identity:	78/432 - (18%)
Similarity:	160/432 - (37%)	Gaps:	108/432 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ADLKYVESAARMIA-EIAQSNKIVVEKST-----------VPVRAAESIMHILRANQKPGIHY-- 150
            ||.:.||||..:.: ...:::.|.::..|           .|....::|...:.|..:|.:..
Zfish   181 ADRRRVESALEVCSLPTGRNDSIPLDTFTQDVYRQLLNNICPRNDIDTIFSDIGAKSRPYLTVEQ 245

  Fly   151 --DILSNPEFLAEGTAINDLLNADRVLIGGEETPEGHQAVEKLSWIYEHWIPKQNILTTNTWSSE 213
              |.|:|.:   ..:.:|::|..             |...|::..:.|.:.|...:.:....|.|
Zfish   246 MTDFLNNKQ---RDSRLNEILYP-------------HLKAEQVQALVEKYEPDSMLSSRGQISVE 294

  Fly   214 -----LS----------KLAANAFLAQRI------SSINSLSAVCEATGADVSEVARAVGLDSRI 257
                 ||          ||..:..:.|.:      ||.|:.....:..|....|:.|.|.|.
Zfish   295 GFARYLSGEENCIIPPEKLDLSEDITQPLSHYFINSSHNTYLIAGQLAGTSSVEIYRQVLLS--- 356

  Fly   258 GSKFLQASVGFGGSCFQKDILNLIYICE---NLNLPEVAAYWQQV------ID-MNEYQKRRFSQ 312
            |.:.::..|..|.:..::.|:...:...   :....::|.|.:::      || :.:|.....||
Zfish   357 GCRCVELDVWKGKAPDEEPIITHGFTMTTEISFKQAKMAEYCRKIFGDALLIDPLEKYPCSSVSQ 421

  Fly   313 KIIESLFNTVSDKRIAI------LGFAFKKNTGDTRETAAITVCQTLLEEGAALD-IYD--PKVE 368
             ||...|  :|:||:.:      :|...     |||..|    .:|...:|.|:: ::|  |.:.
Zfish   422 -IISGQF--LSEKRVGVYVEVEMIGLPV-----DTRWKA----FRTKSSQGNAINPVWDEEPMIF 474

  Fly   369 PEQIIDDLTHPSVTESPEKVKKAVQIHSDPYSAVRATH----------------ALVICTEWDEF 417
            ...::..|....:| :.|...:.:.....|..|:|..:                ::.|.:|..::
Zfish   475 KRVVLPTLASLRIT-AYEDNGRCIGHRIIPVCAIRPGYRYISLRNERNQTLTLPSIFIYSEVKDY 538

  Fly   418 VDLDFKRIYQSMMKPAYIFDGRKILDHERLQQIGFHVQTIGK 459
            |...:..:.:::..|.:..:    |..:|..|:....|..|:
Zfish   539 VPDTYADVIEALSNPIHYVN----LMEQRSHQLAVLTQEEGE 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgl	NP_476980.1	PLN02353	1..459	CDD:177986	77/430 (18%)
LOC100149080	XP_021324223.1	PH_PLC_beta	22..149	CDD:270167
		EFh_PI-PLC	154..304	CDD:333715	25/138 (18%)
		EF-hand motif	154..183	CDD:320029	1/1 (100%)
		EF-hand motif	187..215	CDD:320029	5/27 (19%)
		EF-hand motif	225..254	CDD:320029	6/28 (21%)
		EF-hand motif	271..304	CDD:320029	6/32 (19%)
		PI-PLCc_GDPD_SF	316..>415	CDD:326331	17/101 (17%)
		C2_PLC_like	421..536	CDD:175974	25/127 (20%)
		DUF3084	560..>746	CDD:331293	4/17 (24%)
		DUF1154	644..688	CDD:310911
		PLC-beta_C	720..888	CDD:312287
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000