Protein Alignment CG10077 and PRP28

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_010529.3
• Gene: PRP28 / 851830
• SGDID: S000002651
• Length: 588
• Species: Saccharomyces cerevisiae
• Alignment Length: 471
• Identity: 155/471 - (32%)
• Similarity: 244/471 - (51%)
• Gaps: 47/471 - (9%)

  Fly    97 SSNHGAHLPKIVWSEVNLTPFRKNFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEE 161
            ||..|.|     |:|.:|....:..:        |.:.|....:|      ||..|..|...:||
Yeast   131 SSYMGKH-----WTEKSLHEMNERDW--------RILKEDYAIVT------KGGTVENPLRNWEE 176

  Fly   162 GGF--PDYVMNEIRKQGFAKPTAIQAQGWPIAMS---GRDLVGVAQTGSGKTLAYVLPAVVHINN 221
            ...  .|.:...|::..|..||.||....|...:   .||.:|||.||||||||:|:|.::.::.
Yeast   177 LNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMSR 241

  Fly   222 Q----PRLERGDGPIALVLAPTRELAQQIQQVAIEF------GSNTHVRNTCIFGGAPKGQQARD 276
            .    |.|:..|||.||:|||||||.||||:...:.      .||...:...|.||....:.:..
Yeast   242 SPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFS 306

  Fly   277 LERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQI------RPD 335
            |..|.:|::||||||||.||.....:|:...|||||||:|:|:|||.|:..|:.::      ..:
Yeast   307 LSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVN 371

  Fly   336 RQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDIS 400
            ||.||::||....:.::|..::...:...|| :...:...|.|:|:..|.:|...|.:|   .|.
Yeast   372 RQTLMFTATMTPVIEKIAAGYMQKPVYATIG-VETGSEPLIQQVVEYADNDEDKFKKLK---PIV 432

  Fly   401 AENETKTIIFVETKKRVDEITRNISRQ-GWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVA 464
            |:.:...|||:..|:..|.:.....:: ..:...:||.|||::|:..|..||..:..|::||:||
Yeast   433 AKYDPPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVA 497

  Fly   465 ARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHS-NANKANDLIQVLREANQ 528
            |||||:.:|..|:|:......:||:||||||||:.|.|||.:..:.: :.:...:|.:.:|: :.
Yeast   498 ARGLDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKYVRK-HD 561

  Fly   529 TINPKLMNMAMNGGYN 544
            .:|..:.:.|:...||
Yeast   562 PLNSNIFSEAVKNKYN 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	153/469 (33%)
PRP28	NP_010529.3	SrmB	175..559	CDD:440279	136/387 (35%)