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Protein Alignment CG10077 and DDX59

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001026895.2	Gene:	DDX59 / 83479	HGNCID:	25360	Length:	619	Species:	Homo sapiens

Alignment Length:	425	Identity:	142/425 - (33%)
Similarity:	237/425 - (55%)	Gaps:	10/425 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 TPFRKNF-YKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQGFA 178
            :|...:: ||....:|.....:.|.......|.::|.:|..|.|:||....|:.:.:.::|.|:.
Human   160 SPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYE 224

  Fly   179 KPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPIALVLAPTRELA 243
            .||.||.|..|:.:.|||::..|.||||||.|::||.::.     .|.....|.||:|.||||||
Human   225 VPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR-----ALFESKTPSALILTPTRELA 284

  Fly   244 QQIQQVAIEFGSN-THVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTY 307
            .||::.|.|..|. ..::...:.||.|...|...|::.|:::|||||||:|.:::.:..|.....
Human   285 IQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQSSVELCGVKI 349

  Fly   308 LVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSA 372
            :|:||||.||.|||:.|:..|::.|..|.|.::.|||.|..:.|||.:.|:|.:::..|..:|..
Human   350 VVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPC 414

  Fly   373 NHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISR-QGWRACAIHG 436
             .|:.||:...::..|..||.::|.| ....:...::||:.|...|.::..:.: .|.::.:||.
Human   415 -ANVRQIILWVEDPAKKKKLFEILND-KKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHS 477

  Fly   437 DKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNT 501
            :|||.||..:|.....|.:.::|:|.|..||||:..|:.|:|:|.||:.::|||:|||.||....
Human   478 EKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQN 542

  Fly   502 GTAYTLFTHSNANKANDLIQVLREANQTINPKLMN 536
            |||.|...:::.....|:.:.::.....:.|:|:|
Human   543 GTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN 577

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.