DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10077 and DRH1

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001030619.1	Gene:	DRH1 / 821116	AraportID:	AT3G01540	Length:	619	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	262/566 - (46%)
Similarity:	351/566 - (62%)	Gaps:	58/566 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ANGGQR--RMNGGGPSMGPGGPRNQDGFGGQNGGQRSSNHGAHLPKIVWSEVNLTPFRKNFYKPC 125
            :.|.:|  |.:.||.|    ||...:|..   .|...|.:||...::                |.
plant    85 SRGSERVSRFSEGGRS----GPPYSNGAA---NGVGDSAYGAASTRV----------------PL 126

  Fly   126 DSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQGFAKPTAIQAQGWPI 190
            .|....:....|.:...:|||:.|.|||.|.:.||..|||..::.|:...||:.||.||||.|||
plant   127 PSSAPASELSPEAYSRRHEITVSGGQVPPPLMSFEATGFPPELLREVLSAGFSAPTPIQAQSWPI 191

  Fly   191 AMSGRDLVGVAQTGSGKTLAYVLPAVVH---INNQPRLERGDGPIALVLAPTRELAQQIQQVAIE 252
            ||.|||:|.:|:|||||||.|::|..:|   |.|..|:    ||..|||:||||||.|||:.|::
plant   192 AMQGRDIVAIAKTGSGKTLGYLIPGFLHLQRIRNDSRM----GPTILVLSPTRELATQIQEEAVK 252

  Fly   253 FGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRML 317
            ||.::.:..||::||||||.|.||||||.:||:||||||.|.||....||::.:|||||||||||
plant   253 FGRSSRISCTCLYGGAPKGPQLRDLERGADIVVATPGRLNDILEMRRISLRQISYLVLDEADRML 317

  Fly   318 DMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSL-SLSANHNILQIVD 381
            |||||||||||:::|...||.||::|||||.||::|.:.|.|..|||||:: .|.||.:|.|.::
plant   318 DMGFEPQIRKIVKEIPTKRQTLMYTATWPKGVRKIAADLLVNPAQVNIGNVDELVANKSITQHIE 382

  Fly   382 VCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFV 446
            |....||..:|.::|.  |.|..:|.|||..||:..|::|||::|| :.|.||||||||.|||.|
plant   383 VVAPMEKQRRLEQILR--SQEPGSKVIIFCSTKRMCDQLTRNLTRQ-FGAAAIHGDKSQPERDNV 444

  Fly   447 LSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHS 511
            |:.||:||..:|||||||||||||.|::.|:|||:|:..||||||||||||:..||.|:|.|...
plant   445 LNQFRSGRTPVLVATDVAARGLDVKDIRAVVNYDFPNGVEDYVHRIGRTGRAGATGQAFTFFGDQ 509

  Fly   512 NANKANDLIQVLREANQTINPKLMNMAMNGG-----YNKRGGGMGGGYRGG-NGYQGRNPQMGGG 570
            ::..|:|||::|..|||.:.|::..||..||     :::.|...||..||| :||.||      |
plant   510 DSKHASDLIKILEGANQRVPPQIREMATRGGGGMNKFSRWGPPSGGRGRGGDSGYGGR------G 568

  Fly   571 YNGGNNYRNNNGPGATMNRNSFNGGSAGGPPRFDQKPRTSPPNQGG 616
            .....:.|::||.|....|:.       .|.||::.|   ||:..|
plant   569 SFASRDSRSSNGWGRERERSR-------SPERFNRAP---PPSSTG 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	239/491 (49%)
		DEADc	159..364	CDD:238167	120/207 (58%)
		HELICc	375..507	CDD:238034	73/131 (56%)
DRH1	NP_001030619.1	WW	19..49	CDD:366073
DRH1	NP_001030619.1	PTZ00110	83..549	CDD:240273	239/493 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0331
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X504
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870