Protein Alignment CG10077 and ddx21

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001120807.2
• Gene: ddx21 / 799650
• ZFINID: ZDB-GENE-031113-10
• Length: 791
• Species: Danio rerio
• Alignment Length: 657
• Identity: 174/657 - (26%)
• Similarity: 283/657 - (43%)
• Gaps: 176/657 - (26%)

  Fly   134 GETETFLT----SNEITIKGDQVPTPSIEFEEGGFPDY-----VMNEIRKQGFAKPTAIQAQGWP 189
            |::.|..|    |:..:....:..||  |..||.|.::     .:..::.:|.:....||.:.:.
Zfish   168 GDSHTHSTEPAASSTDSDSEQEKETP--EQREGAFSNFRISPNTIKLLQARGVSYLFDIQVKTFN 230

  Fly   190 IAMSGRDLVGVAQTGSGKTLAYVLPAV--VHINNQPRLERGDGPIALVLAPTRELAQQIQQVAIE 252
            ....|:||:|.|:||:|||.::.:|.|  :...:|.| .||..|..||||||||||.|:.:   :
Zfish   231 AVYDGKDLIGQARTGTGKTFSFAVPLVEKLQSGDQER-RRGRPPKVLVLAPTRELAIQVTK---D 291

  Fly   253 FGSNTH-VRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRM 316
            |...|. :..||.:||:....|...:..|:::::.||||:.|.|:.....|.:..::||||.|:|
Zfish   292 FKDITRKLSVTCFYGGSSYNPQIDAIRSGIDVLVGTPGRIRDHLQNNKLDLSQLQHVVLDEVDQM 356

  Fly   317 LDMGFEPQIRKIMQ-------QIRPDRQVLMWSATWPKEVRQLAEEFL-NNYIQVN-IGSLSLSA 372
            |||||..|:.:|:.       :.:|  |.|::|||.|..|..:|:::: :.:|.|: ||..:..|
Zfish   357 LDMGFAEQVEEILSASYKKDAEQKP--QTLLFSATCPSWVYDVAKKYMRSQFIHVDLIGKKTQKA 419

  Fly   373 NHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNIS-RQGWRACAIHG 436
            ...:..:...|..::: ..:|..:..:.:.:..:||:|.||||...|::.|.| :|.  |.::||
Zfish   420 ATTVEHLAIACHWSQR-ASVIGDVIQVYSGSHGRTIVFCETKKEATELSLNTSIKQS--AQSLHG 481

  Fly   437 DKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNT 501
            |..|::|:..|..||||...:||||:|||||||:.:|..||....|::.|.|:||.|||||:..|
Zfish   482 DIPQKQREVTLKGFRNGSFEVLVATNVAARGLDIPEVDLVIQSSPPNDVESYIHRSGRTGRAGRT 546

  Fly   502 G-------------------------------TAYTLFTHSNANKANDLIQV-------LREANQ 528
            |                               |||.:...|:.:....|..|       .|||.|
Zfish   547 GICICFYQRKEESQLKFVEQKAGITFKRVGVPTAYDIIQSSSKDAVRFLDSVPAVAVGYFREAAQ 611

  Fly   529 TI-------------------------------NPKLMNMAMNGGYNKRGGGMGGGYRGGNGYQG 562
            .:                               .|...:|.::  .::....:...:||.....|
Zfish   612 ELIQQRGAVEALAAALAHISGATSLEQRSLINSEPGFSSMILS--CSQEMHSISFAWRGLKEQLG 674

  Fly   563 RN-----------------------------------------------PQMGGGYNGGNNYRNN 580
            ..                                               |::.......:.:.|:
Zfish   675 EEIDQHISHMVFIKGKKGVCFDVPVSKLKEVQEKWQDSRRWTLSTATQLPELEQSLRPNSGFGNS 739

  Fly   581 NGPGATMNRNSFNGGSAGGPPRFDQKPRTSPPNQGGQG---GYRGQGGGGYQGQQQQQQQQNGGV 642
            .|.|   ||:.| |..:|.        |:...|:||:|   |:|..|.||..||::.
Zfish   740 GGFG---NRSGF-GNRSGN--------RSGFGNRGGRGRSSGFRSSGRGGGGGQKRS-------- 784

  Fly   643 PFSR-FN 648
             ||| ||
Zfish   785 -FSRAFN 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	145/500 (29%)
ddx21	NP_001120807.2	SrmB	200..580	CDD:440279	124/388 (32%)
		GUCT_RHII_Gualpha_beta	629..721	CDD:240593	5/93 (5%)