DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and Tdrd12

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	XP_038956788.1	Gene:	Tdrd12 / 689639	RGDID:	1562792	Length:	1314	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	95/429 - (22%)
Similarity:	176/429 - (41%)	Gaps:	69/429 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 PSIEFEEGGFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHI 219
            |.:..::......:...:::..|..|:...:..||....|.|:|.::..|:...|  .||.::.|
  Rat   420 PCLTLDKSPLSADLKKALQRNKFPGPSHTASYSWPPIARGCDVVVISHCGNDPLL--YLPPLLTI 482

  Fly   220 NNQPRLERG---------DGPIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQAR 275
                 |:.|         :||:|:::.|..:.||.|.::..::..::...:..:........:|:
  Rat   483 -----LQMGGCYKSLPSRNGPLAVIVCPGWKKAQFIFELLGDYSMSSRPLHPVLLTIGLHKDEAK 542

  Fly   276 D--LERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEAD-----------RMLDMGFEPQIRK 327
            :  |.||.::::.||..|:..|...:....|..:|||||..           .:|| .|:..:..
  Rat   543 NMKLPRGCDVIVTTPHSLLRLLTYRSLLFLRLCHLVLDEVHVLFFEANEQMFAILD-NFKKNVEV 606

  Fly   328 IMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANH-NILQIVDVCDENEKLMK 391
            ..::..| .|::.....|.:.:..|..||:.: ..|.|.:|..:|.: ::.|:|.:|.|.||...
  Rat   607 EERESAP-HQIVAVGVHWNRHIEHLVREFMKD-PHVVITALEEAALYGSVQQVVHLCLECEKTST 669

  Fly   392 LIKLLTDISAENETKTIIF----VETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSS--- 449
            |:::| |.......||:||    .||     ||...:.......|.    |..:|..|.|.|
  Rat   670 LLQVL-DFVPSQAQKTLIFTCSVAET-----EIVCKVVESNSIFCL----KMHKEMAFNLKSILE 724

  Fly   450 -----FRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSE----------DYVHRIGRTGRSN 499
                 ..:|.|.:|..||.....|.:.|...|:::.:||:.:          |:...:...|...
  Rat   725 QWKKKLSSGSHIVLTLTDDCIPLLAITDATCVVHFSFPSSPKVFGGRLYCMSDHFQSLTEQGSPA 789

  Fly   500 NTGTAYT----LFTHSNANKANDLIQVLREANQTINPKL 534
            ..|...|    |.|..||:.|..:::.|..|:..|..:|
  Rat   790 EQGGKKTKSVLLLTERNASHAVGVLRYLERADAKIPSEL 828

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	95/429 (22%)
		DEADc	159..364	CDD:238167	44/226 (19%)
		HELICc	375..507	CDD:238034	37/157 (24%)
Tdrd12	XP_038956788.1	Tudor_TDRD12_rpt1	13..171	CDD:410505
		SrmB	428..862	CDD:223587	94/421 (22%)
		Tudor_TDRD12_rpt2	900..1022	CDD:410506
		p23_like	1179..1254	CDD:107220
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0331
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810