DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and Ddx43

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	XP_003750593.1	Gene:	Ddx43 / 682138	RGDID:	1586947	Length:	646	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	190/467 - (40%)
Similarity:	288/467 - (61%)	Gaps:	33/467 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 PKIVWSEV-------------NLTPFRKNFYKPCDSVLARTVGET-------ETF-LTSNEITIK 148
            |.|.|.::             :|.|.:||||  .:|....::.:.       |.| :|.:::. .
  Rat   167 PLIDWDQIREDALKWEKKKWADLPPIKKNFY--IESATTSSMSQVQIDNWRKENFNITCDDLK-D 228

  Fly   149 GDQ--VPTPSIEFEEG--GFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTL 209
            |::  :|.|..:||:.  .:|: ||..|::.||.|||.||:|.|||.:.|.||:||||||:||||
  Rat   229 GEKRPIPNPICKFEDAFHSYPE-VMENIKRAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTL 292

  Fly   210 AYVLPAVVHINNQP-RLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQ 273
            :|::|..:|:::|| ..|:.:||..|||.||||||.|::....:: |...:::.|::||..:..|
  Rat   293 SYLMPGFIHLDSQPLAREQRNGPGMLVLTPTRELALQVEAECSKY-SYGDLKSVCVYGGGDRDGQ 356

  Fly   274 ARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQV 338
            .:|:.:||:|:|||||||.|.......:||..|||||||||:||||||||||.||:..:|||||.
  Rat   357 IQDVSKGVDIIIATPGRLNDLQMNNFVNLKSVTYLVLDEADKMLDMGFEPQIMKILLDVRPDRQT 421

  Fly   339 LMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAEN 403
            :|.|||||..||:||:.:|...:.|.:|:|.|.|...:.|.:.:..|.||...:...|.::|.::
  Rat   422 IMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVKQNIIITTEEEKRTHIQTFLENMSPKD 486

  Fly   404 ETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGL 468
              |.|:||..|...|.::.::..:.....::||::.|.:|:..|.:|:.|:..||:|||:|:|||
  Rat   487 --KVIVFVSRKAVADHLSSDLILRHISVESLHGNREQSDREKALENFKTGKVRILIATDLASRGL 549

  Fly   469 DVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREANQTINPK 533
            ||.|:..|.|||:|.|.|:||||:|||||:..||.:.||.|.::...|.:||.:|..|||.|..:
  Rat   550 DVHDITHVYNYDFPRNIEEYVHRVGRTGRAGRTGMSITLITRNDWRIATELINILERANQNIPEE 614

  Fly   534 LMNMAMNGGYNK 545
            |:.||.....||
  Rat   615 LVLMAERYKANK 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	188/464 (41%)
		DEADc	159..364	CDD:238167	104/207 (50%)
		HELICc	375..507	CDD:238034	49/131 (37%)
Ddx43	XP_003750593.1	KH-I	68..133	CDD:412160
Ddx43	XP_003750593.1	PTZ00110	153..642	CDD:240273	190/467 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910