DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and Ddx55

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_080685.2	Gene:	Ddx55 / 67848	MGIID:	1915098	Length:	600	Species:	Mus musculus

Alignment Length:	412	Identity:	132/412 - (32%)
Similarity:	208/412 - (50%)	Gaps:	59/412 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 VMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAV-VHINNQPRLERGD-G 230
            |:..:|:.||...|.:|:...|:.|..:|:...|.||||||||:|:|.: :.:..:.:|::.. |
Mouse    20 VLGALRELGFPHMTPVQSATIPLFMKNKDVAAEAVTGSGKTLAFVIPILEILLRREEKLKKNQVG 84

  Fly   231 PIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIF-GGAPKGQQARDLER----GVEIVIATPGR 290
              |:|:.||||||.||.:|...|..:....:..:: ||...|:   |:||    |..|::|||||
Mouse    85 --AIVITPTRELAIQIDEVLSHFTKHFPQFSQILWIGGRNPGE---DVERFKQHGGNIIVATPGR 144

  Fly   291 LIDFLERGTTSL------KRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEV 349
            |.|...|....|      |....||||||||:||||||..|..|::.:...|:..::|||..:||
Mouse   145 LEDMFRRKAEGLDLASCVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRTGLFSATQTQEV 209

  Fly   350 RQLAEEFLNNYIQVNIGSLSLSA-----------NHNILQIVDVCDENEKLMKLIKLLTDISAEN 403
            ..|....|.|.:::::....::|           ||.:     :|..:||..:|:..|   .:..
Mouse   210 ENLVRAGLRNPVRISVKEKGVAASSTQKTPSRLENHYM-----ICKADEKFNQLVHFL---RSRQ 266

  Fly   404 ETKTIIFVET-------KKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVAT 461
            :.|.::|..|       .|.::.:.:.:     :...||| |.:.:|:.:...||..:..|||.|
Mouse   267 QEKHLVFFSTCACVEYYGKALEALLKKV-----KILCIHG-KMKYKRNKIFMEFRKLQSGILVCT 325

  Fly   462 DVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDL------- 519
            ||.|||:|:.:|.:|:.||.|||:..:|||.|||.|..:.|:|............|.|
Mouse   326 DVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLLPMEEAYINFLAINQKCP 390

  Fly   520 IQVLREANQTIN--PKLMNMAM 539
            :|.:.....||:  |||..||:
Mouse   391 LQEMSLQRNTIDLLPKLRAMAL 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	132/412 (32%)
		DEADc	159..364	CDD:238167	77/208 (37%)
		HELICc	375..507	CDD:238034	42/138 (30%)
Ddx55	NP_080685.2	DEADc	9..224	CDD:238167	77/208 (37%)
		Q motif	9..37		5/16 (31%)
		DEXDc	24..228	CDD:214692	76/208 (37%)
		DEAD box	171..174		2/2 (100%)
		Helicase_C	252..363	CDD:278689	39/119 (33%)
		DUF4217	403..462	CDD:290667	5/10 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	499..551
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0331
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900