DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10077 and bel

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster

Alignment Length:	750	Identity:	271/750 - (36%)
Similarity:	365/750 - (48%)	Gaps:	150/750 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GGGG----GGGAGGLAGGMVPNRMGGGAPGGG-PGGAGMFQRNRSAPYPG----------FNGHG 61
            ||||    |||.||..........|.|:.||| .||.|.|:.|    |.|          :|..|
  Fly    95 GGGGEYRRGGGGGGRGFNRQSGDYGYGSGGGGRRGGGGRFEDN----YNGGEFDSRRGGDWNRSG 155

  Fly    62 PANGGQRRMNGGGPSMGPGG----------------------PRNQ--------DGFGGQNGGQ- 95
            ...||.|.. |.|||...||                      |||.        .||.|..|||
  Fly   156 GGGGGGRGF-GRGPSYRGGGGGSGSNLNEQTAEDGQAQQQQQPRNDRWQEPERPAGFDGSEGGQS 219

  Fly    96 ----RSSNH------GAHLPKIVWSE-----VNLTPFRKNFYKPCDSVLARTVGETETFLTSN-- 143
                ||.|:      |.:..:  |.|     |:.|.....     |..|     |.|.|...|
  Fly   220 AGGNRSYNNRGERGGGGYNSR--WKEGGGSNVDYTKLGAR-----DERL-----EVELFGVGNTG 272

  Fly   144 -------EITIK--GDQVPTPSIEFEEGGFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVG 199
                   :|.::  |..||.....|::....:.:.|.:....:.|||.:|....||.::||||:.
  Fly   273 INFDKYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMA 337

  Fly   200 VAQTGSGKTLAYVLP------AVVHI----NNQPRLERGDGPIALVLAPTRELAQQIQQVAIEFG 254
            .||||||||.|:::|      .:.|:    :.:....|...|:.||||||||||.||.:.|.:|.
  Fly   338 CAQTGSGKTAAFLVPILNQMYELGHVPPPQSTRQYSRRKQYPLGLVLAPTRELATQIFEEAKKFA 402

  Fly   255 SNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDM 319
            ..:.:|...::||....:|.|:|:||..:::||||||.|.:.||...|:...:||||||||||||
  Fly   403 YRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDM 467

  Fly   320 GFEPQIRKIMQQIR----PDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIV 380
            |||||||:|::|:.    ..||.||:|||:||::::||.:||:|||.:.:|.:. |.:.||.|.:
  Fly   468 GFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVG-STSENITQTI 531

  Fly   381 DVCDENEKLMKLIKLLTDISAENE-TK---TIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQ 441
            ....|.:|...|:.||:.|....| ||   |:|||||||..|.:...:.:......:||||::|:
  Fly   532 LWVYEPDKRSYLLDLLSSIRDGPEYTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQK 596

  Fly   442 ERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYT 506
            ||:..|..||:|...|||||.|||||||:..||.|||:|.||:.|:||||||||||..|.|.|.:
  Fly   597 EREEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATS 661

  Fly   507 LFTHSNANKANDLIQVLREANQTINPKLMNMAMNGGYNKRGGGMGGGYRGGNGYQGRNPQMGGGY 571
            .|...|.|..:||:::|.|..|.|...:.:|:.:.|:       ||..|.|.|..||   .|||:
  Fly   662 FFNEKNRNICSDLLELLIETKQEIPSFMEDMSSDRGH-------GGAKRAGRGGGGR---YGGGF 716

  Fly   572 NGGNNYRNNNGPGATMNRNSFNGGSAGGPPRFDQKPRTSPPNQGGQGG-YR-----------GQG 624
             |..:||.::|.|         ||...|||     ||:.....||.|| ||           ..|
  Fly   717 -GSRDYRQSSGGG---------GGGRSGPP-----PRSGGSGSGGGGGSYRSNGNSYGKFGGNSG 766

  Fly   625 GGGYQGQQQQQQQQNGGVPFSRFNPNAACFEPNKP 659
            ||||.|     ....||.....:...:|....|.|
  Fly   767 GGGYYG-----GGAGGGSYGGSYGGGSASHSSNAP 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	214/579 (37%)
		DEADc	159..364	CDD:238167	94/218 (43%)
		HELICc	375..507	CDD:238034	66/135 (49%)
bel	NP_001262379.1	DEADc	297..516	CDD:238167	94/218 (43%)
		DEXDc	315..529	CDD:214692	96/214 (45%)
		Helicase_C	538..654	CDD:278689	59/115 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451403
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	280	1.000	Inparanoid score	I100
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9764
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990