DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and pit

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001287459.1	Gene:	pit / 42595	FlyBaseID:	FBgn0266581	Length:	680	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	123/382 - (32%)
Similarity:	204/382 - (53%)	Gaps:	26/382 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 EGGFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINN---Q 222
            :|...:..:..|::.||.:.|.||::.....:.||||||.||||||||||:::|||..||.   .
  Fly   191 KGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFM 255

  Fly   223 PRLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIAT 287
            ||    :|...::::|||||:.|...|..|..::.|.....:.||:.:..::..|.:|:.|::||
  Fly   256 PR----NGTGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVESEKLGKGINILVAT 316

  Fly   288 PGRLIDFLERGTTSL-KRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQ 351
            ||||:|.|:.....| |....|::||.||:|::|||.::::|:..:...||.:::|||....:..
  Fly   317 PGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTARIEA 381

  Fly   352 LAEEFLNN---YIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVET 413
            |::..|.:   |:.|:....:.:.: .:.|...|| .:||  :|:.|.|.:....:.|.::|..:
  Fly   382 LSKLALKSEPIYVGVHDNQDTATVD-GLEQGYIVC-PSEK--RLLVLFTFLKKNRKKKVMVFFSS 442

  Fly   414 KKRV---DEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKF 475
            ...|   .|:...|...   ..:|||.:.|.:|......|.|....||:.|||||||||:..|.:
  Fly   443 CMSVKYHHELFNYIDLP---VTSIHGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDW 504

  Fly   476 VINYDYPSNSEDYVHRIGRTGRSNNT-GTAYTLFTHSNANKANDLIQVLREANQTIN 531
            ::.||.|.:..:|:||:|||.|.:.| |.|..|.......    .::.|:.|...:|
  Fly   505 IVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELG----FLRYLKAAKVPLN 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	123/382 (32%)
		DEADc	159..364	CDD:238167	73/209 (35%)
		HELICc	375..507	CDD:238034	45/135 (33%)
pit	NP_001287459.1	SrmB	186..677	CDD:223587	123/382 (32%)
		DEADc	187..394	CDD:238167	72/206 (35%)
		HELICc	408..537	CDD:238034	45/134 (34%)
		DUF4217	569..627	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840