Protein Alignment CG10077 and ddx5

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_989229.1
• Gene: ddx5 / 394837
• XenbaseID: XB-GENE-1009995
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 657
• Identity: 351/657 - (53%)
• Similarity: 420/657 - (63%)
• Gaps: 80/657 - (12%)

  Fly    55 PGFNGHGPANGGQRRMNGGGPSMGPGGPRNQDGFGGQNGGQ--RSSNHGAHLPKIVWSEVNLTPF 117
            ||||....|     |..|.|     ||||    |||..||.  :..|.|..|.|..|:...|..|
 Frog     2 PGFNDRDRA-----RDRGFG-----GGPR----FGGNRGGTSGKYGNPGERLMKKKWNLDELPKF 52

  Fly   118 RKNFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQGFAKPTA 182
            .||||:....|:.||..|.:.:..|.|||::|...|.|.::|.|..||..:|..:::|.|..||.
 Frog    53 EKNFYQEHPDVVRRTPQECDQYRRSKEITVRGLNCPKPVLQFHEASFPANLMEVVKRQNFTDPTP 117

  Fly   183 IQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPIALVLAPTRELAQQIQ 247
            ||.||||:|:||.|:||||.|||||||:|:||.:||||:||.|:||||||.||||||||||||:|
 Frog   118 IQGQGWPVALSGLDMVGVAMTGSGKTLSYLLPGIVHINHQPFLQRGDGPILLVLAPTRELAQQVQ 182

  Fly   248 QVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDE 312
            |||.|:|....:|:|||:||||||.|.|||||||||.||||||||||||.|.|:|.|||||||||
 Frog   183 QVAAEYGRACRLRSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAGKTNLNRCTYLVLDE 247

  Fly   313 ADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNIL 377
            ||||||||||||||||:.|||||||.||||||||||||||||:||.:|:.:|||:|.||||||||
 Frog   248 ADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYVHINIGALELSANHNIL 312

  Fly   378 QIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQE 442
            ||||||::.||..||::|:.:|.:|.|.|||:|||||:|.|::||.:.|.||.|..|||||||||
 Frog   313 QIVDVCNDGEKDEKLVRLMEEIMSEKENKTIVFVETKRRCDDLTRRLRRDGWPAMGIHGDKSQQE 377

  Fly   443 RDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTL 507
            ||:||:.|::|:..||:|||||:|||||:|||||||||||::||||:||||||.||:.||||||.
 Frog   378 RDWVLNEFKHGKSPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSSKTGTAYTF 442

  Fly   508 FTHSNANKANDLIQVLREANQTINPKLMNMAMN-------GGYNKRGGGMGGGYRGGNGYQGRNP 565
            ||..|..:.||||.|||||||.|||||:.:..:       ||.|.|......|.|||...:..:.
 Frog   443 FTPGNIKQVNDLISVLREANQAINPKLLQLVEDRGRFRGRGGMNDRRDRFSSGKRGGWDRENYDR 507

  Fly   566 QMGGGYNGGNNYRN------NNGPGA-TMNRNSFNGGSAGGPPRFDQKPRTSPPNQGGQGGYR-G 622
            ..||..:.||..:|      .||.|| ..|.||||  |.|               ...|.|:| |
 Frog   508 GFGGKRDFGNKSQNGFGNKSQNGFGAQNYNGNSFN--SYG---------------TNVQSGFRAG 555

  Fly   623 QGGGGYQGQQQQQQQQNGGVPFSRFNPNAACFEPNKPQNGPGSGPPQAQHQQQQQAQAAQQQHLL 687
            ...|.||.....|                        ||| .|.||       .|...|||.:..
 Frog   556 AQNGTYQNGYASQ------------------------QNG-YSAPP-------MQNSMAQQAYTY 588

  Fly   688 PDASVQA 694
            |.|:..|
 Frog   589 PAATATA 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	308/497 (62%)
ddx5	NP_989229.1	DEAD-like_helicase_N	33..499	CDD:475120	295/465 (63%)