Protein Alignment CG10077 and ddx46

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001019988.2
• Gene: ddx46 / 321948
• ZFINID: ZDB-GENE-030131-667
• Length: 1035
• Species: Danio rerio
• Alignment Length: 721
• Identity: 219/721 - (30%)
• Similarity: 360/721 - (49%)
• Gaps: 111/721 - (15%)

  Fly   111 EVNLTPFRKNFYKPCDSVLARTVGE--TETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIR 173
            ::...|||||||..... |||...|  :|..|....|::||...|.|...:.:.|....|:|.::
Zfish   310 KIQYEPFRKNFYVEVPE-LARMSPEEVSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLNALK 373

  Fly   174 KQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPIALVLAP 238
            |..:.|||.||||..|..||||||:|:|:||||||:|::||...||.:|..:...:||:|:::.|
Zfish   374 KHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPVGEAEGPLAVIMTP 438

  Fly   239 TRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERG---TT 300
            |||||.||.:...:|..:..:|..|::||....:|..:|:||.||::.||||:||.|...   .|
Zfish   439 TRELALQITKECKKFSKSLALRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVT 503

  Fly   301 SLKRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNI 365
            :|:|.||:|:||||||.|||||||:.:|:..:|||||.:|:|||:|:.:..||...|:..::|.:
Zfish   504 NLRRVTYVVIDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQV 568

  Fly   366 GSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWR 430
            |..|:..: ::.|.|.|.:|.:|.:||:::|...  :.:...||||:.::..|.:.:::.:..:.
Zfish   569 GGRSVVCS-DVEQHVIVIEEEKKFLKLLEILGHY--QEKGSVIIFVDKQEHADGLLKDLMKASYP 630

  Fly   431 ACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRT 495
            ..::||...|.:||.:::.|:||...:||||.||||||||..:..|:||..|::.||||||.|||
Zfish   631 CMSLHGGIDQYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRT 695

  Fly   496 GRSNNTGTAYTLFTHSNANKANDLIQVLREANQTINPKLMNMAMNGGYNKRGGGMGGGYRGGNGY 560
            ||:.|.|.|||..|...|..:.|:::.|..:..::..:|..:..|  :.::....|...:..:|:
Zfish   696 GRAGNKGYAYTFITEGQARYSGDILKALELSGSSVPAELEQLWTN--FKEQQKAEGKIIKSSSGF 758

  Fly   561 QGR-------------------------------------NPQMGGGYNGGNNYRNNNGPGATMN 588
            .|:                                     :.|:...:|.....::.:.||
Zfish   759 SGKGFKFDETEHALANERKKLQKAALGLHDSDDEDTALDIDEQIESMFNSKKRVKDFSAPG---- 819

  Fly   589 RNSFNGGSAGGPPRFDQKPRTSPPNQGGQGGYRGQGGGGYQGQQ-------QQQQQQNGGVPFSR 646
              |.:.|||||       ...|.....|.|.......|..|..:       :.|.|:|.|.
Zfish   820 --SVSAGSAGG-------VSGSVSAVSGLGSLSTPSAGNIQKLEIAKKLALRIQAQKNLGA---- 871

  Fly   647 FNPNAACFEPNKPQNGPGSGPPQAQHQQQQQAQAAQQQHLLPDASVQAAMTAANYGVDQKRSRFS 711
                                  :||...||...|     :|...::.|...:|....:|:..:.:
Zfish   872 ----------------------EAQDVMQQATNA-----ILRGGTIIAPSVSAKTIAEQQAEKIN 909

  Fly   712 PYNMNFANMPPPAMNQQQAAAAQ--QQQQQQLQT---PQQQQQQQQMQQP-QAYGQYSSMSSSMA 770
            . .:|:..:......:|.|.||:  ::.:::|:.   ||..:.:...::. |..|:||.     |
Zfish   910 A-KLNYTPVEKLEEERQAAEAAETVKRYEEELEINDFPQTARWKVTSKEALQRIGEYSE-----A 968

  Fly   771 TVSLNG 776
            .:::.|
Zfish   969 AITIRG 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	174/437 (40%)
ddx46	NP_001019988.2	Q motif	357..385		8/27 (30%)
		DEAD box	514..517		2/2 (100%)