Protein Alignment CG10077 and ddx4

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_073769595.1
• Gene: ddx4 / 30263
• ZFINID: ZDB-GENE-990415-272
• Length: 796
• Species: Danio rerio
• Alignment Length: 613
• Identity: 218/613 - (35%)
• Similarity: 311/613 - (50%)
• Gaps: 96/613 - (15%)

  Fly     2 NMYNGQMNAFGGG--GGGGAGGLAGGMVPNRMGGGAPGGG--PGGAGMFQRNRSAPYPGFNGHGP 62
            |..||..:.:.||  .|.|.||..||.    .||...||.  .|..|..:.|.........|.|.
Zfish   197 NDENGNDDGWKGGESRGRGRGGFGGGF----RGGFRDGGNEDTGRRGFGRENNENGNDEGEGRGR 257

  Fly    63 ANGGQRR--MNGGGPSMGPGGPRNQDGFGGQN-------------GGQRSSNHGAHLPKIVW--- 109
            ..||.|.  .:|||...|..| ..:.||.|:|             ..:.|.|.|   ||:|:
Zfish   258 GRGGFRGGFRDGGGDESGKRG-FGRGGFRGRNEEVFSKVTTADKLDQEGSENAG---PKVVYVPP 318

  Fly   110 --SEVNLTPFRK-----NFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDY 167
              .|...:.|..     ||.| .|.:|               :.:.|...|...:.|||.|..|.
Zfish   319 PPPEEESSIFSHYATGINFDK-YDDIL---------------VDVSGSNPPKAIMTFEEAGLCDS 367

  Fly   168 VMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLER--GDG 230
            :...:.|.|:.|||.:|..|.||..:||||:..||||||||.|::||.         |:|  .||
Zfish   368 LSKNVSKSGYVKPTPVQKHGIPIISAGRDLMACAQTGSGKTAAFLLPI---------LQRFMTDG 423

  Fly   231 -----------PIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIV 284
                       |.|:::||||||..||...|.:|...|.||...::||...|...|::.:|..::
Zfish   424 VAASKFSEIQEPEAIIVAPTRELINQIYLEARKFAYGTCVRPVVVYGGINTGYTIREVLKGCNVL 488

  Fly   285 IATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIRKIM----QQIRPDRQVLMWSATW 345
            .||||||.|.:.||...|.:..|||||||||||||||||::||::    ...:.:||.||:|||:
Zfish   489 CATPGRLHDLIGRGKIGLSKVRYLVLDEADRMLDMGFEPEMRKLVASPGMPSKEERQTLMFSATY 553

  Fly   346 PKEVRQLAEEFLN-NYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTII 409
            |::::::|.:||. :||.:.:|.:. .|..::.|.:...|:..|..:|::||   .|....:|::
Zfish   554 PEDIQRMAADFLKVDYIFLAVGVVG-GACSDVEQTIVQVDQYSKRDQLLELL---RATGNERTMV 614

  Fly   410 FVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVK 474
            |||||:..|.|...:.::.....:||||:.|:||:..||.||.|:..:||||.|||||||::.|:
Zfish   615 FVETKRSADFIATFLCQEKISTTSIHGDREQREREKALSDFRLGQCPVLVATSVAARGLDIEQVQ 679

  Fly   475 FVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFT-HSNANKANDLIQVLREANQTINPKLMNMA 538
            .|:|:|.||:.::||||||||||..|||.|.:.|. .|:...|..|::||..|.|.:...|..:|
Zfish   680 HVVNFDMPSSIDEYVHRIGRTGRCGNTGRAVSFFNPESDTPLARSLVKVLSGAQQVVPKWLEEVA 744

  Fly   539 MNG----GYNKRG-------GGMGGGYR 555
            .:.    |:|.||       ...||.::
Zfish   745 FSAHGTTGFNPRGKVFASTDSRKGGSFK 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	196/542 (36%)
ddx4	XP_073769595.1	None