DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and Ddx23

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001100263.2	Gene:	Ddx23 / 300208	RGDID:	1308685	Length:	819	Species:	Rattus norvegicus

Alignment Length:	459	Identity:	180/459 - (39%)
Similarity:	257/459 - (55%)	Gaps:	49/459 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 WSEVNLTPFRKNFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIR 173
            ||:           |..|.:..|   :...|.....||.||.::|.|...:::...|.:::..|.
  Rat   356 WSQ-----------KKLDEMTDR---DWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVID 406

  Fly   174 KQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLER----GDGPIAL 234
            |.|:.:||.||.|..||.:..||::|||:||||||.|:::|.:|.|...|:::|    ..||.|:
  Rat   407 KCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAI 471

  Fly   235 VLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGT 299
            :|||||||||||::..|:||....:|...:.||..:..|...|..|.||||||||||||.||...
  Rat   472 ILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRY 536

  Fly   300 TSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQI-----RPD---------------------RQV 338
            ..|.||||:||||||||:||||||.::||::.:     :||                     ||.
  Rat   537 LVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQT 601

  Fly   339 LMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAEN 403
            :|::||.|..|.:||..:|.....|.|||.. ..:..:.|.|.:..|:||..||:.:|   ....
  Rat   602 VMFTATMPPAVERLARSYLRRPAVVYIGSAG-KPHERVEQKVFLMSESEKRKKLLAIL---EQGF 662

  Fly   404 ETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGL 468
            :...||||..||..|.:.:::.:.|:.||.:||.|.|::|:|.||:.:.|...||||||||.||:
  Rat   663 DPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGI 727

  Fly   469 DVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREAN-QTINP 532
            |:.||..|:|||...|.|||:||||||||:..:|.|.|..|..::....:|.|.:.|:. .:..|
  Rat   728 DIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPP 792

  Fly   533 KLMN 536
            :|.|
  Rat   793 ELAN 796

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	180/459 (39%)
		DEADc	159..364	CDD:238167	98/234 (42%)
		HELICc	375..507	CDD:238034	58/131 (44%)
Ddx23	NP_001100263.2	SF-CC1	79..>207	CDD:273721
		DEADc_DDX23	401..627	CDD:350703	97/225 (43%)
		SF2_C_DEAD	638..767	CDD:350174	59/131 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D183201at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920