Protein Alignment CG10077 and Ddx3y

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_036138.1
• Gene: Ddx3y / 26900
• MGIID: 1349406
• Length: 658
• Species: Mus musculus
• Alignment Length: 615
• Identity: 235/615 - (38%)
• Similarity: 322/615 - (52%)
• Gaps: 84/615 - (13%)

  Fly    57 FNGHGPANGGQRRMNGGGPSMGPGGPRNQDGFG--GQNGGQRSSNHGAHLPKIVWSEVNLTPFRK 119
            |:..|..:.|:...:|.....|.|| |::.|||  .::|..|.|:..   .:..||: .|.|..:
Mouse    85 FSDRGSGSRGRFDDHGRNDYDGIGG-RDRTGFGKFERSGHSRWSDRS---DEDDWSK-PLPPSER 144

  Fly   120 -------------NFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIE-FEEGGFPDYVMN 170
                         ||.|..|..:..|                |:..| |.|| |.:....:.:|.
Mouse   145 LEQELFSGGNTGINFEKYDDIPVEAT----------------GNNCP-PHIENFSDIEMGEIIMG 192

  Fly   171 EIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHI-------------NNQ 222
            .|....:.:||.:|....||....|||:..||||||||.|::||.:..|             .|.
Mouse   193 NIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAMKENG 257

  Fly   223 PRLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIAT 287
            ....|...||:||||||||||.||.:.|.:|...:.||...::|||...||.||||||..:::||
Mouse   258 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVAT 322

  Fly   288 PGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQ--IRPD--RQVLMWSATWPKE 348
            ||||:|.:|||...|..|.||||||||||||||||||||:|::|  :.|.  |..:|:|||:|||
Mouse   323 PGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKE 387

  Fly   349 VRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVET 413
            ::.||.:||:.||.:.:|.:. |.:.||.|.|...:|.:|...|:.||.  :...::.|::||||
Mouse   388 IQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEELDKRSFLLDLLN--ATGKDSLTLVFVET 449

  Fly   414 KKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVIN 478
            ||..|.:...:.::.:...:||||:||::|:..|..||:||..|||||.|||||||:.:||.|||
Mouse   450 KKGADSLENFLFQERYACTSIHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVIN 514

  Fly   479 YDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREANQTINPKLMNMAMNGGY 543
            :|.||:.|:||||||||||..|.|.|.:.|...|.|...||:.:|.||.|.:...|.:||....|
Mouse   515 FDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLESMAYEHHY 579

  Fly   544 NKRGGGMGGGYRGGNGYQGRNPQMGGGYNGGNNYRNNNG-PGATMNRNSFNGGSAGGPPRFDQKP 607
            .       |..||.:     ..:..||: |..:||.::| ..|..|.|..|...:.|
Mouse   580 K-------GSSRGRS-----KSRFSGGF-GARDYRQSSGSANAGFNSNRANSSRSSG-------- 623

  Fly   608 RTSPPNQG-GQGGYRG-QGGGGYQGQQQQQ 635
              |..|:| |.|||.| ....||.|....|
Mouse   624 --SSHNRGFGGGGYGGFYNNDGYGGNYNSQ 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	208/519 (40%)
Ddx3y	NP_036138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..143		18/62 (29%)
		DEADc_DDX3	159..409	CDD:350809	113/267 (42%)
		Q motif	179..207		6/27 (22%)
		DEAD box	346..349		2/2 (100%)
		SF2_C_DEAD	414..544	CDD:350174	62/131 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..627		9/39 (23%)