DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10077 and Ddx46

DIOPT Version :9

Sequence 1:NP_001261491.1 Gene:CG10077 / 38756 FlyBaseID:FBgn0035720 Length:818 Species:Drosophila melanogaster
Sequence 2:NP_620798.1 Gene:Ddx46 / 245957 RGDID:708480 Length:1032 Species:Rattus norvegicus


Alignment Length:470 Identity:188/470 - (40%)
Similarity:278/470 - (59%) Gaps:25/470 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 NHGAHLPKIVWSEVNLTPFRKNFYKPCDSVLARTVGETETF-LTSNEITIKGDQVPTPSIEFEEG 162
            :||         ::...|||||||.....:...:..|...| |....||:||...|.|...:.:.
  Rat   322 DHG---------KIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQC 377

  Fly   163 GFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLER 227
            |....::|.::|.|:.|||.||.|..|..||||||:|:|:||||||:|::||...||.:|..||.
  Rat   378 GISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEE 442

  Fly   228 GDGPIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLI 292
            |:||||:::.||||||.||.:...:|.....:|..|::||....:|..:|:||.||::.||||:|
  Rat   443 GEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507

  Fly   293 DFLERGT---TSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAE 354
            |.|...:   |:|:|.||:||||||||.|||||||:.:|:..:|||||.:|:|||:|:.:..||.
  Rat   508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALAR 572

  Fly   355 EFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDE 419
            ..|:..|:|.:|..|:..: ::.|.|.|.:|.:|.:||::||...  :.....||||:.::..|.
  Rat   573 RILSKPIEVQVGGRSVVCS-DVEQQVIVIEEEKKFLKLLELLGHY--QESGSVIIFVDKQEHADG 634

  Fly   420 ITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSN 484
            :.:::.|..:...::||...|.:||.:::.|:||...:||||.||||||||..:..|:||..|::
  Rat   635 LLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNH 699

  Fly   485 SEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREANQTINPKLMNM--------AMNG 541
            .||||||.|||||:.|.|.|||..|...|..|.|:|:.|..:...:.|.|..:        ...|
  Rat   700 YEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEG 764

  Fly   542 GYNKRGGGMGG-GYR 555
            ...|:..|..| |::
  Rat   765 KIIKKSSGFSGKGFK 779

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10077NP_001261491.1 PTZ00110 49..544 CDD:240273 184/456 (40%)
DEADc 159..364 CDD:238167 99/207 (48%)
HELICc 375..507 CDD:238034 54/131 (41%)
Ddx46NP_620798.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..227
SrmB 344..826 CDD:223587 179/439 (41%)
Q motif 372..400 8/27 (30%)
DEADc 378..581 CDD:238167 99/202 (49%)
DEAD box 529..532 2/2 (100%)
Helicase_C 618..714 CDD:278689 41/95 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D245118at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.920

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