DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and sacy-1

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_491962.1	Gene:	sacy-1 / 172413	WormBaseID:	WBGene00019245	Length:	630	Species:	Caenorhabditis elegans

Alignment Length:	473	Identity:	184/473 - (38%)
Similarity:	262/473 - (55%)	Gaps:	38/473 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 ITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQ-GFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKT 208
            |:.:||.:|.|...|.|..||..::..::|| |...|||||.||.|:|:||||::|:|.||||||
Worm   177 ISCEGDHIPPPIGSFLEMKFPKSLLEFMQKQKGIVTPTAIQIQGIPVALSGRDMIGIASTGSGKT 241

  Fly   209 LAYVLPAVVH-INNQPRLE--RGDGPIALVLAPTRELAQQIQQVAIEF-------GSNTHVRNTC 263
            :.:|||.|:. :..:.:|.  |.:||..|::.|:||||:||..:.||.       |........|
Worm   242 MTFVLPLVMFCLEQEMKLPFMRSEGPFGLIIVPSRELARQIFDLIIEMFDALGKAGLPEMRAGLC 306

  Fly   264 IFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIRKI 328
            | ||.|.|:||:|:..|:.||:||||||.|.|.:...:|:.|.||||||||||||||||.:|:.|
Worm   307 I-GGVPIGEQAKDVRDGIHIVVATPGRLSDMLTKKIINLEVCRYLVLDEADRMLDMGFEDEIKSI 370

  Fly   329 MQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLI 393
            ....:..||.|::|||.|::::..|:..|...|.||:|... :|:.|:||.::......||::::
Worm   371 FYFFKAQRQTLLFSATMPRKIQFFAKSALVKPIVVNVGRAG-AASLNVLQELEFVRSENKLVRVL 434

  Fly   394 KLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSIL 458
            :.|...|    .|.:||.|.|..||.|...:..:|....:|||.|.|.:|...:.:||.....:|
Worm   435 ECLQKTS----PKVLIFAEKKVDVDNIYEYLLVKGVEVASIHGGKDQSDRHAGIEAFRKNEKDVL 495

  Fly   459 VATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFT-HSNANKANDLIQV 522
            ||||||::|||...::.|||:|.|.:.|:|||||||||||...|.|.|... .|..:..:||.|:
Worm   496 VATDVASKGLDFQGIEHVINFDMPEDIENYVHRIGRTGRSGRKGLATTFINKKSEMSVLSDLKQL 560

  Fly   523 LREANQTINPKLMNMAMNGGYNKRGGGMGGGYRGGNGYQGRNPQMGGGYNGGNNYRNNNGP---- 583
            |.||.|.: |:.:.|.             .|...|....|.|.:.|..|..|..:|..:.|
Worm   561 LAEAGQEL-PEFLKML-------------AGDEEGTAPAGTNAEKGCAYCSGLGHRITDCPKLAG 611

  Fly   584 --GATMNRNSFNGGSAGG 599
              ..|....:..||..||
Worm   612 IGNKTTQALARGGGDDGG 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	170/410 (41%)
		DEADc	159..364	CDD:238167	97/215 (45%)
		HELICc	375..507	CDD:238034	53/131 (40%)
sacy-1	NP_491962.1	DEADc	191..406	CDD:238167	97/215 (45%)
		DEXDc	206..410	CDD:214692	96/204 (47%)
		HELICc	416..544	CDD:238034	53/131 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	1	1.010	-	-		D183201at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930