Protein Alignment CG10077 and Ddx4

DIOPT Version :10

• Sequence 1: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_011242920.1
• Gene: Ddx4 / 13206
• MGIID: 102670
• Length: 738
• Species: Mus musculus
• Alignment Length: 605
• Identity: 204/605 - (33%)
• Similarity: 304/605 - (50%)
• Gaps: 90/605 - (14%)

  Fly    11 FGGGGGGGAGGLAGGMVPNRMGGGAPG-------GGPGGAGMFQRNRSAPYPGFNGHGPANGGQR 68
            |..||.|...|..||     .|.|.|.       |...|.|:|...:.|          |:...:
Mouse   151 FRRGGRGSFRGCRGG-----FGLGRPNSESDQDQGTQRGGGLFGSRKPA----------ASDSVQ 200

  Fly    69 RMNGGGPSMGPGGPRNQDGFGGQN-----------------GGQRSSNHGAHLPKIVWSEVNLTP 116
            .:.|.|.:........:.|:.|.|                 ||:.|.:.|   ||:.
Mouse   201 CLTGNGDTYQSRSGSGRGGYKGLNEEVVTGSGKNSWKSETEGGESSDSQG---PKVT-------- 254

  Fly   117 FRKNFYKPC------DSVLAR-----TVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMN 170
                 |.|.      ||:.|.     ...:.:|.|    :.:.|...|...:.|||......:.|
Mouse   255 -----YIPPPPPEDEDSIFAHYQTGINFDKYDTIL----VEVSGHDAPPAILTFEEANLCQTLNN 310

  Fly   171 EIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQ----PRLERGDGP 231
            .|.|.|:.|.|.:|....||.::||||:..||||||||.|::||.:.|:...    .|.:....|
Mouse   311 NIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEP 375

  Fly   232 IALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLE 296
            ..:::||||||..||...|.:|...|.||...|:||...|...|.:.:|..|:.||||||:|.:.
Mouse   376 ECIIVAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSVRQIVQGCNILCATPGRLMDIIG 440

  Fly   297 RGTTSLKRCTYLVLDEADRMLDMGFEPQIRKIM----QQIRPDRQVLMWSATWPKEVRQLAEEFL 357
            :....||:..|||||||||||||||.|:::|::    ...:..||.|::|||:|:|:::||.:||
Mouse   441 KEKIGLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGDFL 505

  Fly   358 -NNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEIT 421
             ::|:.|.:|.:. .|..::.|.:....:..|..||:::|.:|..|   :|::||||||:.|.|.
Mouse   506 KSSYLFVAVGQVG-GACRDVQQTILQVGQYSKREKLVEILRNIGDE---RTMVFVETKKKADFIA 566

  Fly   422 RNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSE 486
            ..:.::.....:||||:.|:||:..|..||.|:..:||||.|||||||:::|:.|||:|.||..:
Mouse   567 TFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTID 631

  Fly   487 DYVHRIGRTGRSNNTGTAYTLF-THSNANKANDLIQVLREANQTINPKLMNMAMNG------GYN 544
            :||||||||||..|||.|.:.| |.|:.:.|..|::||.:|.|.:...|..:|.:.      ..:
Mouse   632 EYVHRIGRTGRCGNTGRAISFFDTDSDNHLAQPLVKVLSDAQQDVPAWLEEIAFSTYVPPSFSSS 696

  Fly   545 KRGGGMGGGYRGGNGYQGRN 564
            .|||.:.........|||::
Mouse   697 TRGGAVFASVDTRKNYQGKH 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	184/538 (34%)
Ddx4	XP_011242920.1	DEADc_DDX4	266..518	CDD:350810	97/255 (38%)
		SF2_C_DEAD	524..653	CDD:350174	59/131 (45%)