DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10077 and ddx41

DIOPT Version :9

Sequence 1:	NP_001261491.1	Gene:	CG10077 / 38756	FlyBaseID:	FBgn0035720	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	XP_012815277.1	Gene:	ddx41 / 100491281	XenbaseID:	XB-GENE-967537	Length:	621	Species:	Xenopus tropicalis

Alignment Length:	457	Identity:	171/457 - (37%)
Similarity:	259/457 - (56%)	Gaps:	22/457 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 KNFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQGFAKPTAI 183
            |..:||...:|..:....:...:...|.::|:::|.|...|:|..||..::..::|:|...||.|
Frog   142 KTSWKPPRHILEMSEARHDRVRSKYHILVEGERIPQPIKSFKEMKFPAAILRGLKKKGIHHPTPI 206

  Fly   184 QAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVH-INNQPRL--ERGDGPIALVLAPTRELAQQ 245
            |.||.|..:||||::|:|.|||||||.:.||.::. :..:.||  .:.:||..|::.|:||||:|
Frog   207 QIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFAKREGPYGLIICPSRELARQ 271

  Fly   246 IQQVAIEF-------GSNTHVRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERGTTSLK 303
            ...: ||:       .:..|:|.....||....:|...:::||.:::||||||:|.|::...||.
Frog   272 THSI-IEYYCHLLQEDNFPHLRTALCIGGMSVKEQMETIKQGVHMMVATPGRLMDLLQKKMVSLD 335

  Fly   304 RCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSL 368
            .|.||.|||||||:|||||..||.|....:..||.|::|||.||:::..|:..|...|.:|:|..
Frog   336 ICRYLALDEADRMIDMGFEEDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPITINVGRA 400

  Fly   369 SLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACA 433
            . :|:.:::|.|:...|..|::.|::.|    .:.....:||.|.|..||.|...:..:|..|.|
Frog   401 G-AASLDVIQEVEYVKEEAKMVYLLECL----QKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVA 460

  Fly   434 IHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRS 498
            |||.|.|:||...:.:||..:..:|||||||::|||...::.|:|||.|...|:|||||||||||
Frog   461 IHGGKDQEERTKAIEAFREEKKDVLVATDVASKGLDFPAIQHVVNYDMPEEIENYVHRIGRTGRS 525

  Fly   499 NNTGTAYTLFTHS-NANKANDLIQVLREANQTINPKLMNMAMNGGYNKR---GGGMGGGYRGGNG 559
            .|||.|.|....| :.:...||..:|.||.|.:.|.|  ..:||.....   |...|..:.||.|
Frog   526 GNTGIATTFINKSCDESVLMDLKALLMEAKQRVPPVL--QVLNGSDETMLDIGDERGCAFCGGLG 588

  Fly   560 YQ 561
            ::
Frog   589 HR 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	166/435 (38%)
		DEADc	159..364	CDD:238167	87/214 (41%)
		HELICc	375..507	CDD:238034	56/131 (43%)
ddx41	XP_012815277.1	DEADc	182..396	CDD:238167	87/214 (41%)
		DEXDc	195..408	CDD:214692	86/214 (40%)
		Helicase_C	417..526	CDD:278689	48/112 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	1	1.010	-	-		D183201at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930