Protein Alignment CG10077 and Ddx43

DIOPT Version :9

• Sequence 1: NP_001261491.1
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001177973.1
• Gene: Ddx43 / 100048658
• MGIID: 3642857
• Length: 646
• Species: Mus musculus
• Alignment Length: 595
• Identity: 215/595 - (36%)
• Similarity: 324/595 - (54%)
• Gaps: 62/595 - (10%)

  Fly     6 GQMNAFGGGGG-----GGAGGLAGGM--------VPNRMGGGAPGGGPGGAGMFQRNRSAPYPGF 57
            |::.:.|.|||     |.|...|.|.        |.|.:.|...|.|.......|...:......
Mouse    39 GRVGSRGAGGGWREPAGAAEATAAGRREPPLCFGVKNDVVGAVIGRGGSKIREIQNTTNTRIQVI 103

  Fly    58 NGHGPAN---GGQRRMNGGGPSMGPGGPRNQDGF-GGQN----------GGQRSSNHGA--HLPK 106
            .|:..|.   .|.:.|.....::.....:.|..: .||.          |...|::...  ..|.
Mouse   104 KGNPEAEIKIFGNKAMQTKAKTVIDNVVKKQQNYIPGQRVGIIAFQPTVGADTSTSESVTDDQPL 168

  Fly   107 IVWSEV-------------NLTPFRKNFYKPCDSVLARTVGET-------ETF-LTSNEITIKGD 150
            |.|.::             :|.|.:||||  .:|....::.:.       |.| :|.:::. .|:
Mouse   169 IDWDQIREDALKWEKKKWADLPPIKKNFY--IESATTSSMSQVQIDNWRKENFNITCDDLK-DGE 230

  Fly   151 Q--VPTPSIEFEEGGFPDY--VMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAY 211
            :  :|.|..:||: .|..|  ||..|::.||.|||.||:|.|||.:.|.||:||||||:||||:|
Mouse   231 KRPIPNPICKFED-AFQSYPEVMENIKRAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLSY 294

  Fly   212 VLPAVVHINNQP-RLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTHVRNTCIFGGAPKGQQAR 275
            ::|..:|:::|| ..|:.:||..|||.||||||.|::....:: |...:::.|::||..:..|.:
Mouse   295 LMPGFIHLDSQPLAREQRNGPGMLVLTPTRELALQVEAECSKY-SYGDLKSVCVYGGGDRDGQIQ 358

  Fly   276 DLERGVEIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLM 340
            |:.:||:|:|||||||.|.......:||..|||||||||:||||||||||.||:..:|||||.:|
Mouse   359 DVSKGVDIIIATPGRLNDLQMNNFVNLKSVTYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTIM 423

  Fly   341 WSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENET 405
            .|||||..||:||:.:|...:.|.:|:|.|.|...:.|.:.:..|.||...:...|.::|.::
Mouse   424 TSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAVSTVKQNIIITTEEEKRTHIQTFLENMSPKD-- 486

  Fly   406 KTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDV 470
            |.|:||..|...|.::.::..:.....::||::.|.:|:..|.:|:.|:..||:|||:|:|||||
Mouse   487 KVIVFVSRKAVADHLSSDLILRHISVESLHGNREQSDREKALENFKTGKVRILIATDLASRGLDV 551

  Fly   471 DDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREANQTINPKLM 535
            .|:..|.|||:|.|.|:||||:|||||:..||.:.||.|.::...|.:||.:|..|||.|..:|:
Mouse   552 HDITHVYNYDFPRNIEEYVHRVGRTGRAGRTGMSITLITRNDWRVATELINILERANQNIPEELV 616

  Fly   536 NMAMNGGYNK 545
            .||.....||
Mouse   617 LMAERYKANK 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10077	NP_001261491.1	PTZ00110	49..544	CDD:240273	198/536 (37%)
		DEADc	159..364	CDD:238167	105/207 (51%)
		HELICc	375..507	CDD:238034	49/131 (37%)
Ddx43	NP_001177973.1	KH-I	73..127	CDD:238053	10/53 (19%)
		DEADc	249..446	CDD:238167	101/197 (51%)
		DEXDc	255..453	CDD:214692	102/198 (52%)
		HELICc	461..588	CDD:238034	49/128 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910