Protein Alignment CG14820 and AGBL4

DIOPT Version :9

• Sequence 1: NP_648060.1
• Gene: CG14820 / 38754
• FlyBaseID: FBgn0035718
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_011540610.1
• Gene: AGBL4 / 84871
• HGNCID: 25892
• Length: 531
• Species: Homo sapiens
• Alignment Length: 458
• Identity: 85/458 - (18%)
• Similarity: 153/458 - (33%)
• Gaps: 161/458 - (35%)

  Fly    10 GLFGLARSVEQVRYD----------------NYKVYNVRIDDLEQ------------FKLLH-TQ 45
            |..|....|.:..||                |:.|.||:...:.:            |.::: ::
Human    53 GNLGRVDQVSEFEYDLFIRPDTCNPRFRVWFNFTVENVKESQVREIVDTFRVVLRVIFNIVNFSK 117

  Fly    46 ERSLKLSSWREARHLGESSDIMLP-------PEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRP 103
            .:||    :|         |.|.|       |::|:              |...||..:......
Human   118 TKSL----YR---------DGMAPMVKSTSRPKWQR--------------LPPKNVYYYRCPDHR 155

  Fly   104 KQRITSMEWTQFHTLEEIYA--------------WLDVIEDRYPDIVTPFTIGNSYEGRPIRGVK 154
            |..:.|..:. |...|:||.              :||.::.|..|......:|.|.:.|.:..:.
Human   156 KNYVMSFAFC-FDREEDIYQFAYCYPYTYTRFQHYLDSLQKRNMDYFFREQLGQSVQQRKLDLLT 219

  Fly   155 I----SYKEG--NPAVFIESNIHARE-----------------------------WITSATITYF 184
            |    :.:||  ...|||...:|..|                             |::...|
Human   220 ITSPDNLREGAEQKVVFITGRVHPGETPSSFVCQGIPPGHWAALSSSFQNSPGIHWMSPGII--- 281

  Fly   185 IDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFD 249
              :.||.::|....:.:.:.:.|.|:||.||....:     :|.|         .:|.||||:
Human   282 --DFLVSQHPIACVLREYLVFKIAPMLNPDGVYLGN-----YRCS---------LMGFDLNRH-- 328

  Fly   250 YLWMLTGAESDPCSQLYAGPSPESDPE---ISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWG 311
              |:              .|||...|.   :.||...:.|. |:.:::.||.:|::...:.....
Human   329 --WL--------------DPSPWVHPTLHGVKQLIVQMYND-PKTSLEFYIDIHAHSTMMNGFMY 376

  Fly   312 HTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEV-SGSGKEW-AYAVKNIKIHYT 374
            ....|..|.:.:.....|     |..:....|:|.|::.....| :|:|:.: ...:.:....||
Human   377 GNIFEDEERFQRQAIFPK-----LLCQNAEDFSYSSTSFNRDAVKAGTGRRFLGGLLDHTSYCYT 436

  Fly   375 IEL 377
            :|:
Human   437 LEV 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	13/88 (15%)
		M14_CP_A-B_like	115..410	CDD:199844	62/317 (20%)
AGBL4	XP_011540610.1	M14_AGBL4_like	190..475	CDD:133118	58/293 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810