DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and Agbl3

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001276585.1	Gene:	Agbl3 / 76223	MGIID:	1923473	Length:	1006	Species:	Mus musculus

Alignment Length:	371	Identity:	70/371 - (18%)
Similarity:	108/371 - (29%)	Gaps:	162/371 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 EYQKTFE-SLLT-KHNFTYNLKIDNVQ-------THIDAQRPK---------------------- 104
            ||:.|.. .|.| ||...|..::.|.|       |.::..:|.
Mouse   195 EYELTVRPDLFTNKHTQWYYFQVTNTQAEIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNI 259

  Fly   105 --QRI------------------TSMEWT-QF-HTLEEIYAWLDVIEDRYPDIVTPFTIGNSYE- 146
              |||                  .|:.|| || |:.:..|     ....|     |:|..|..|
Mouse   260 GWQRIGDQIKYYKNNLGQDGRHFFSLTWTFQFPHSQDTCY-----FAHCY-----PYTYSNLQEY 314

  Fly   147 -----GRPIRG-------------------------VKISYKEGNPAVFIESNIHAREWITSATI 181
                 ..|:|.                         :|.|..: ..||.:.:.:|..|..:|..:
Mouse   315 LSGINSDPVRSKFCKIRVLCHTLARNMVYVLTITTPLKTSDSK-RKAVILTARVHPGETNSSWIM 378

  Fly   182 TYFIDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNR 246
            ..|:|.:|...:.| |.:.....:.::|:||.||....:     :|.|         ..|.||||
Mouse   379 KGFLDYILGDSSDA-RLLRDTFIFKVVPMLNPDGVIVGN-----YRCS---------LAGRDLNR 428

  Fly   247 NFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWG 311
            |                  |.....||.|.:......||..:.:..:.:|..||          |
Mouse   429 N------------------YTSLLKESFPSVWYTRNMINRLMEKREVILYCDLH----------G 465

  Fly   312 HTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSG 357
            |:                        |...:|.||...::..:..|
Mouse   466 HS------------------------RKQNIFMYGCDGSSRSKTKG 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	11/37 (30%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	51/275 (19%)
Agbl3	NP_001276585.1	M14_AGBL2-3_like	315..576	CDD:133117	43/241 (18%)
Agbl3	NP_001276585.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900