DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and Agtpbp1

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001364026.1	Gene:	Agtpbp1 / 67269	MGIID:	2159437	Length:	1218	Species:	Mus musculus

Alignment Length:	408	Identity:	78/408 - (19%)
Similarity:	123/408 - (30%)	Gaps:	167/408 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GLARSVEQVRYDNYKV---------------------------YNVRIDDLE----QFK-----L 41
            |..|.|.|:|...|.:                           |...|.:.|    ||.     |
Mouse   711 GNLRKVIQIRKSEYDLILNSDINSNHYHQWFYFEVSGMRPGVAYRFNIINCEKSNSQFNYGMQPL 775

  Fly    42 LHTQERSLKLSSW---------REARHLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNV--- 94
            :::.:.:|....|         ....|...|| :....:..|::.::....||.:.   |:|
Mouse   776 MYSVQEALNARPWWIRMGTDICYYKNHFSRSS-VAAGGQKGKSYYTITFTVNFPHK---DDVCYF 836

  Fly    95 -----QTHIDAQRPKQRITSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPF-TI-----GNSYEGR 148
                 .|:...|...|::.|.     |..::||...||:.:.....:.|. ||     .|.||
Mouse   837 AYHYPYTYSTLQMHLQKLESA-----HNPQQIYFRKDVLCETLSGNICPLVTITAMPESNYYE-- 894

  Fly   149 PIRGVKISYKEGNPAVFIESNIHARE----WITSATITYFIDELLVPRNPAVRDIAQNVDWYIIP 209
                 .|......|.:|:.:.:|..|    |:...|:.|     |:..:|..:.:.::..:.|:|
Mouse   895 -----HICQFRTRPYIFLSARVHPGETNASWVMKGTLEY-----LMSNSPTAQSLRESYIFKIVP 949

  Fly   210 VLNTDGFAYSHEVERLWRKSRLPSDPTGEC--IGTDLNRNFDYLWMLTGAESDPCSQLYAGPSPE 272
            :||.||....:.                .|  .|.||||.    |.              .|:||
Mouse   950 MLNPDGVINGNH----------------RCSLSGEDLNRQ----WQ--------------SPNPE 980

  Fly   273 SDPEI---SQLTAYINNSIPEGTIK----IYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKG 330
            ..|.|   ..|..|:      ..:|    :|...|          ||:
Mouse   981 LHPTIYHAKGLLQYL------AAVKRLPLVYCDYH----------GHS----------------- 1012

  Fly   331 FSDALYRRYGTVFTYGSS 348
                   |...||.||.|
Mouse  1013 -------RKKNVFMYGCS 1023

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	16/94 (17%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	52/253 (21%)
Agtpbp1	NP_001364026.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	476..512
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	590..617
		Pepdidase_M14_N	704..838	CDD:407865	22/130 (17%)
		M14_Nna1	861..1131	CDD:349477	51/249 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1193..1218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900