DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and CG8560

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	157/433 - (36%)
Similarity:	229/433 - (52%)	Gaps:	40/433 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLKILLVVGLF-GLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREA-------R 58
            :||:..||.|. .:|.:||  .||.||:|::...:..:.:||      |:||. .||       |
  Fly     1 MLKLFAVVLLLASVALAVE--NYDGYKIYDINARNAFEKQLL------LRLSG-NEAYDFFDLPR 56

  Fly    59 HLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPK---QRI-------TSMEWT 113
            .|..||.:|:.||.|:.||.||.|:...|::..:|....:..:|.:   ||:       .|:.:.
  Fly    57 SLDASSRVMVKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFK 121

  Fly   114 QFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISY---KEGNPAVFIESNIHAREW 175
            .||...||.|:||.:...||..|:....|.|||.|.|:.:.|:.   |.|...||:::.||||||
  Fly   122 AFHRHAEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREW 186

  Fly   176 ITSATITYFIDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECI 240
            |..|...|.|.: ||....|..::.::.||.|:||:|.||:.|||...|:|||:|.|.  :..|.
  Fly   187 IAHAGALYVIHQ-LVENFAANSELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPI--SSACY 248

  Fly   241 GTDLNRNFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQY 305
            |||.|||||:.|...||.|..||..:.|.:..|:|| :||...|..|: .|..|.|::|||||.|
  Fly   249 GTDANRNFDFHWGEVGASSYSCSDTFKGETAFSEPE-TQLIRDILLSL-TGRGKFYLTLHSYGNY 311

  Fly   306 VLSPWGHTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIK 370
            :|.|||.|: ..|..:.....||:|.:||:....||.:|.|||...||..:|...::|:.|.|..
  Fly   312 LLYPWGWTS-ALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFP 375

  Fly   371 IHYTIELRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREI 413
            :..|:|| ..|..||   ......:...|:|.:||:.|.|:::
  Fly   376 VSITMEL-PAGGTGF---NPSTSQIEGFVSETWVGIKAMAQKV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	22/75 (29%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	117/297 (39%)
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	22/75 (29%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	118/300 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466992
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.800