DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14820 and CG18417

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	134/428 - (31%)
Similarity:	218/428 - (50%)	Gaps:	32/428 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ILLVVGLFGLARSVEQV-RYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREA---RHLGESSD 65
            ::|.:....|:..:::. :|:.||:|.|. .:.............:|.:|:.|.   .:.|....
  Fly     6 VILALSCLSLSAGLQRTNKYEGYKIYEVS-SEARSVAFSEALSELVKNASYYEVFSELNAGNPGK 69

  Fly    66 IMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQRITSMEW---------TQFHTLEEI 121
            ||:.|..|..|..|:.::|..|::...||...:..|....|:. ..|         .:::..|||
  Fly    70 IMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRML-RHWFPYNGRLGTERYYNHEEI 133

  Fly   122 YAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKIS---YKEGNPAVFIESNIHAREWITSATITY 183
            ..:::.:...:|..|...|:|.|||||.::.:.|:   .:.....:.::...||||||:.|..||
  Fly   134 NQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAREWISPAAATY 198

  Fly   184 FIDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSH--EVERLWRKSRLPSDPTGECIGTDLNR 246
            .|::|:....... |:..:.||.|:||:|.||:.|:.  |..|:|||:|.||  :.:|||||.||
  Fly   199 LINQLVYNLEDNA-DLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPS--SSDCIGTDPNR 260

  Fly   247 NFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWG 311
            |||:.|...||..|||..:|||..|.|:||...:...|::.:..|  ::|::|||||..:|.|||
  Fly   261 NFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRG--QMYLTLHSYGSLILYPWG 323

  Fly   312 HTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTL-YEVSGSGKEWAYAVKNIKIHYTI 375
            .|| ..|:....:..||.....|:....||::..|.||||: |..||:..::|:.. ...|.:|:
  Fly   324 WTA-AVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNA-GFPISFTM 386

  Fly   376 ELRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREI 413
            || ..|..||..|..||..:.:|.   :||:.|.||::
  Fly   387 EL-PFGGTGFDPPASDIDSIVKET---WVGIAAMARKV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	15/71 (21%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	108/300 (36%)
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416	10/33 (30%)
CG18417	NP_648119.1	M14_CP_A-B_like	127..420	CDD:199844	110/303 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466984
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.750