DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and CG18585

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	190/420 - (45%)
Similarity:	260/420 - (61%)	Gaps:	8/420 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLKILLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLH-TQERSLKLSSWREARHLGESSD 65
            ||..|:.:...|:.:...:.||||::||.:.|.:..|...:. ..|.:.|.:.|:|........|
  Fly     6 LLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDERSRQID 70

  Fly    66 IMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQR--PKQRITSMEWTQFHTLEEIYAWLDVI 128
            ||:.|.....|:.||..:|.:..|.|:|||..||.::  |.....:..||:::.||||.||||.|
  Fly    71 IMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSATFGWTKYYELEEIEAWLDEI 135

  Fly   129 EDRYPDIVTPFTIGNSYEGRPIRGVKISYKEGNPAVFIESNIHAREWITSATITYFIDELLVPRN 193
            .:.||.:...|.:|.|||||.|||:|||:|.|||.:|||||||||||||||:.|:||::||...:
  Fly   136 LNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPGIFIESNIHAREWITSASATWFINQLLTSED 200

  Fly   194 PAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWML-TGA 257
            ..||.:|.|.||:||||.|.|||.|||:.:|:|||:|.| ..|..|||.|.|||||..|:. .||
  Fly   201 ADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQP-HATNACIGADANRNFDSYWLQNNGA 264

  Fly   258 ESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGHTALEFPEHYP 322
            ..:|||:.:||.:|||:||...|..|:...  :..|.:|||.||||||:|||:|||..||||:|.
  Fly   265 SDNPCSETFAGDNPESEPEAKALVEYLTKI--QDQISVYISFHSYGQYLLSPYGHTNEEFPENYN 327

  Fly   323 QMMHVAKGFSDALYR-RYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIELRDKGELGFV 386
            .::.:.|.|:||:.. .||||:.|||:|..||..:|:..:|.:.....||.||||.||||..||:
  Fly   328 DILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFI 392

  Fly   387 LPPEDIIPVAREVTEGFVGMIAAAREIDIL 416
            |||..|||...|:..|.:.:|...:|:..|
  Fly   393 LPPVQIIPNCEELMVGMLALIEKTKELGYL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	20/69 (29%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	154/296 (52%)
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	20/70 (29%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	154/295 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468813
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2817
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	11	10.800