DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14820 and CG3097

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_572259.1	Gene:	CG3097 / 31503	FlyBaseID:	FBgn0029804	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	137/435 - (31%)
Similarity:	222/435 - (51%)	Gaps:	50/435 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLKILLVVGLFGL--------------ARSVEQVRYDN---YKVYNVRIDDLEQFKLLHTQERS 48
            |||::||:|.....              |..:.| |||.   :::||:.....::..:....|:.
  Fly     6 MLLQLLLLVAAVAASLANELPSNLTLLDANEIPQ-RYDEAQLWRIYNISEAMQKRVPVGQMLEQK 69

  Fly    49 LKLSSWRE-ARHLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHID------------- 99
            ...:.|:| ::.|    ||.:..:..|...|.|:.|.....:...|:|:.||
  Fly    70 FGGNIWKENSKFL----DISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFG 130

  Fly   100 -AQRPKQRI-TSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYK-EGN 161
             .:|.|:.. :||.|..:|.||.||:::..|..::|:||..:|||.:.|||.::.::||.. ..|
  Fly   131 HGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPREN 195

  Fly   162 PAVFIESNIHAREWITSATITYFIDELLV--PRNPA-VRDIAQNVDWYIIPVLNTDGFAYSHEVE 223
            ..|:|:..|||||||:.||:|:.:.:|:.  ...|| :|.:.    |||:||:|.||:.||....
  Fly   196 KKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIRGLT----WYIMPVMNPDGYEYSRTTN 256

  Fly   224 RLWRKSRLPSDPTGECIGTDLNRNFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSI 288
            |||||:|.|| ...:|.|.|||||||..|...|:.::|||..|.|.:|.|:.|...:..::...
  Fly   257 RLWRKNRSPS-RRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKR- 319

  Fly   289 PEGTIKIYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLY 353
             :..::.|::.|||||.::.||.:.|::..: ...:..|:...::.:.::.||.:....:...|.
  Fly   320 -KYNLESYLTFHSYGQMIVYPWAYKAVKVKD-ASVLQRVSSLAAERILQKTGTSYRAAVTHEVLG 382

  Fly   354 EVSGSGKEWAYAVKNIKIHYTIELRDKGELGFVLPPEDIIPVARE 398
            ...|...:|:.|...:|..|||||||:|..||||||..|...|.|
  Fly   383 IAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	14/83 (17%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	105/288 (36%)
CG3097	NP_572259.1	Propep_M14	64..118	CDD:280416	13/57 (23%)
CG3097	NP_572259.1	M14_CP_A-B_like	148..439	CDD:199844	105/288 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466953
Domainoid	1	1.000	225	1.000	Domainoid score	I2535
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	10	9.900