DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and SPBC337.07c

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_595408.1	Gene:	SPBC337.07c / 2541067	PomBaseID:	SPBC337.07c	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	417	Identity:	112/417 - (26%)
Similarity:	191/417 - (45%)	Gaps:	43/417 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREARHLGESSDIMLPPEYQKTFES 78
            |:..:::.:..|..:::...|.::    |..:|.:...  |:....    |||::....:..|||
pombe    89 LSDILQKAQSQNLDIWDYNFDHVD----LRLKEENFDF--WKSQYR----SDILINNLTETLFES 143

  Fly    79 LL---TKHNFTYNLKIDNVQT-HIDAQRPKQRITSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPF 139
            ::   |...|:....:..|:. |::.:. ....|.:.:..:..||.|.:||.::...|.|:....
pombe   144 IVPDTTNSPFSTEAFLQAVENGHLNHEM-FTSFTDIFFKSYQNLESINSWLRLMASLYKDLSELV 207

  Fly   140 TIGNSYEGRPIRGVKISYK---------EGNPAVFIESNIHAREWITSATITYFIDELLV--PRN 193
            .:|.:.|||.|.|:|::.:         .....:.|:...||||||...::.|...:||.  ..:
pombe   208 PVGITAEGRTILGLKLNGRHPSDNGEKIRNKKVIIIQGGSHAREWIGIPSVCYAAWQLLAKYDSD 272

  Fly   194 PAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWMLTGAE 258
            ..||.:....:|..|||||.||:.|:...:|||.|:|.|.: ..||.|.:|:.|:.:.:   ...
pombe   273 GHVRKLLDKFEWIFIPVLNVDGYEYTWSNDRLWSKNRQPLN-NSECFGINLDANWAFGF---NGN 333

  Fly   259 SDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKI--YISLHSYGQYVLSPWGHTALEFPEHY 321
            .||||..|.|.||....|...|...|..|:.:...|:  ::.:|||.|.||.|:.:|...||...
pombe   334 IDPCSNEYGGLSPFQANETMALFNLITESLSQEQKKVVGFLDVHSYSQSVLWPYAYTCDLFPPDT 398

  Fly   322 PQMMHVAKGFSDALYRRYGTVFTYGSSATTLYE------VSGSGKEWAYAVKNIKIHYTIELRDK 380
            .....:|.|....|:|.....:|| ..|...|:      :.|:..:|.|...::...:.|.|||.
pombe   399 ENFEELAIGLVKELHRVNSRYYTY-QQACIPYDGFHKHYLPGTAIDWVYFAADVAWPFNIRLRDM 462

  Fly   381 GELGFVLPPEDIIPVAREVTEGFVGMI 407
            |:.|::||.:.|:|.|:|    |..||
pombe   463 GDYGYLLPAKQIVPTAKE----FFAMI 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	14/72 (19%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	95/312 (30%)
SPBC337.07c	NP_595408.1	MpaA	42..479	CDD:225421	107/405 (26%)
SPBC337.07c	NP_595408.1	M14_CP_A-B_like_1	180..492	CDD:199869	95/315 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
TreeFam	0	0.000	Not matched by this tool.
	9	8.860