DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and Agbl5

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_036020907.1	Gene:	Agbl5 / 231093	MGIID:	2441745	Length:	1007	Species:	Mus musculus

Alignment Length:	427	Identity:	87/427 - (20%)
Similarity:	141/427 - (33%)	Gaps:	135/427 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 TYNLKIDNVQTH-------IDAQRPKQRITSMEWTQFHTLEEIYAWLD---VIEDRYPDIVTPFT 140
            |::..:|::..|       :|.    .|:..:..|..|.|.:     |   .:|..:||:.||
Mouse   302 THSSPLDSIYYHRELLCYSLDG----LRVDLLTITSCHGLRD-----DREPRLEQLFPDLGTP-- 355

  Fly   141 IGNSYEGRPIRGVKISYKEGNPAVFIESNIHAREWITSATITYFIDELLVPRNPAVRDIAQNVDW 205
                   ||.|..      |....|:.|.:|..|..:|.....|:|.:|.|.:|..:.:.:...:
Mouse   356 -------RPFRFT------GKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVF 407

  Fly   206 YIIPVLNTDG------------------------------------FAYSHEVERLWRKSRLPSD 234
            .:||:||.||                                    ..|.|...||..||.....
Mouse   408 KLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNAKSPTNQQ 472

  Fly   235 PT----GECIGTDLNR-----NFDYLWM-------LTGAESDPCSQ----LYAGPSPESDPEISQ 279
            ||    .|...:||.:     |..:|..       .|..|::|..:    ::..|.|     |.:
Mouse   473 PTLHLPPEAPLSDLEKANNLHNEAHLGQSPDGENPATWPETEPAEEKTDPVWLMPQP-----IPE 532

  Fly   280 LTAYINNSIP--EGTIKIYISLHSY----GQYVLSPWGHTALEFPEH--------YPQMMHVAKG 330
            |.....::||  |..:..|:.||.:    |.::   :|::   |.:.        ||:::.:...
Mouse   533 LEEPAPDTIPPKESGVAYYVDLHGHASKRGCFM---YGNS---FSDESTQVENMLYPKLISLNSA 591

  Fly   331 FSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIE---------------LRDK 380
            ..|.....:.....|...........|||:...|....|...||:|               ..|.
Mouse   592 HFDFQGCNFSEKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDN 656

  Fly   381 GELGFVLPPEDIIPVAREVTEGF--VGMIAAAREIDI 415
            |...  .||....| :|...|.|  ||...|...:|:
Mouse   657 GRAS--PPPPPAFP-SRYTVELFEQVGRAMAIAALDM 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	3/20 (15%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	79/384 (21%)
Agbl5	XP_036020907.1	Pepdidase_M14_N	102..>214	CDD:407865
Agbl5	XP_036020907.1	M14_AGBL5_like	304..695	CDD:349455	86/425 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900