Protein Alignment CG14820 and CPA3

DIOPT Version :10

• Sequence 1: NP_648060.1
• Gene: CG14820 / 38754
• FlyBaseID: FBgn0035718
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 136/405 - (33%)
• Similarity: 227/405 - (56%)
• Gaps: 14/405 - (3%)

  Fly     3 LKILLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSW--REARHLGESS- 64
            ::::|.|||.....::..||:|..||:.|:..|.:|..::....::.:|..|  ....|:..:.
Human     1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMM 65

  Fly    65 -DIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQ-RPKQRITSM-EWTQFHTLEEIYAWLD 126
             |..:..:..:..:|.|.::...|.:.|.::|..|:.| ..|:.|... .:.:::..|:|.||.:
Human    66 VDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWEKIVAWTE 130

  Fly   127 VIEDRYPDIVTPFTIGNSYEGRPIRGVKISYK-EGNPAVFIESNIHAREWITSATITYFIDEL-- 188
            .:.|:||::|:...||::.|..|:..:||..| |...|:|.:..||||||::.|...:|:.:.
Human   131 KMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATK 195

  Fly   189 LVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWM 253
            ...||..:..:...:::||:||.|.||:.:|....|:|||:| ..:...:||||||||||:..|.
Human   196 TYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNR-SKNQNSKCIGTDLNRNFNASWN 259

  Fly   254 LTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGHTALEFP 318
            .....:|||:..|.|.:|||:.|...:|.:|.:.:.|  ||:||:.|||.|.:|.|:|:|: :.|
Human   260 SIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNE--IKVYITFHSYSQMLLFPYGYTS-KLP 321

  Fly   319 EHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIELRDKGEL 383
            .::..:..|||..:|.|..||.|.:.||...:|:|.:|||..:|||.: .||..:..||||||:.
Human   322 PNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDL-GIKHTFAFELRDKGKF 385

  Fly   384 GFVLPPEDIIPVARE 398
            ||:||...|.|..||
Human   386 GFLLPESRIKPTCRE 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	29..101	CDD:460505	13/75 (17%)
		M14_CP_A-B_like	115..406	CDD:349433	111/287 (39%)
CPA3	NP_001861.2	Propep_M14	27..103	CDD:460505	13/75 (17%)
		M14_CPB	114..413	CDD:349443	111/292 (38%)