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Protein Alignment CG14820 and CPA2

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	426	Identity:	131/426 - (30%)
Similarity:	228/426 - (53%)	Gaps:	24/426 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLKILLVVG-LFGLARSVEQVRYDNYKVYNVRIDDLEQFK---LLHTQERSLKLSSWREARHLG 61
            |.::::|..| |||....:|....|  :|..:...:.||.|   .|..||. |:|..|:.....|
Human     1 MAMRLILFFGALFGHIYCLETFVGD--QVLEIVPSNEEQIKNLLQLEAQEH-LQLDFWKSPTTPG 62

  Fly    62 ESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQ-------RPKQRITSMEWTQFHTLE 119
            |::.:.:|....:..:..|......|::.|::||..:|.:       |.::|..:..:..:||||
Human    63 ETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLE 127

  Fly   120 EIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEGNPAVFIESNIHAREWITSATITYF 184
            ||...:|.:...:|.:|:...||:|:|.||:..:|.|.....||:::::.||||||:|.||..:.
Human   128 EISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWT 192

  Fly   185 IDELL--VPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGE-CIGTDLNR 246
            .::::  ..::|::..|...:|.:::||.|.||:.:|....|:|||:|  |..:|. |:|.|.||
Human   193 ANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTR--SKVSGSLCVGVDPNR 255

  Fly   247 NFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWG 311
            |:|..:...||.|:|||..|.|||..|:.|:..:..:|.:   .|.:|.:|:||||.|.::.|:|
Human   256 NWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS---HGKVKAFITLHSYSQLLMFPYG 317

  Fly   312 HTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIE 376
            :...:. :.:.::..||:..:.:|...:||.:..|...:.:|:.||...:|:|.. .||..:..|
Human   318 YKCTKL-DDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDY-GIKYSFAFE 380

  Fly   377 LRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAARE 412
            |||.|..||:||...|:|.|.|...|...::...|:
Human   381 LRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 416

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.