DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14820 and LOC105947369

DIOPT Version :9

Sequence 1:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_012818774.2	Gene:	LOC105947369 / 105947369	-ID:	-	Length:	419	Species:	Xenopus tropicalis

Alignment Length:	434	Identity:	136/434 - (31%)
Similarity:	231/434 - (53%)	Gaps:	41/434 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLKILLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREARHLGESSD 65
            |.:.||.||.:..||....: |:||.|...|...:.|..:.:....|.::|:.|:.     .||.
Frog     1 MKIVILFVVIVASLAAPFIR-RFDNEKALRVFPQNEEDVQFIKHLARVMQLNFWKP-----HSSS 59

  Fly    66 IMLP---------PEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQ-----RPK-QRITSMEWTQF 115
            .::|         .|.......||.:....:.:...|:|..|:.|     .|| :|..|   .::
Frog    60 YVIPKAFVDFHANAEDSHIITGLLEEKGIKHRILFQNLQEAIENQLSKAGNPKDERFPS---PRY 121

  Fly   116 HTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKI----SYKEGNPAVFIESNIHAREWI 176
            .|..||..|...:..:||::|:....||:|||:.|..:|:    ::|:|   :.:|..:||||||
Frog   122 RTWLEISTWAYRVSVKYPNLVSVVQAGNTYEGQTILVLKVGSQSAHKKG---IVLECGVHAREWI 183

  Fly   177 TSATITYFIDELL--VPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGEC 239
            :.|...:|::|.:  ..::.|:..:..:|.::::||.|.||:.::...:|:|||:|. .|...:|
Frog   184 SPAFCQWFVNEAIRSYGKDKAMTKLLNSVTFHVVPVFNVDGYIWTWTHDRMWRKNRY-QDANNKC 247

  Fly   240 IGTDLNRNFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQ 304
            :|.||||||:..|....:..:|||::|||..|||:.|...:.:||.::|  .::|.|||.|:|||
Frog   248 VGVDLNRNFNASWGTGFSNDEPCSEIYAGSGPESENETKAVASYIRDNI--SSLKAYISFHAYGQ 310

  Fly   305 YVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNI 369
            .::.|:|:.: |.|.:..::..:|.....||...|||.:|:|..|||:|.||||..:|||. :.:
Frog   311 MLMYPYGYKS-EKPPNSKKLDKIAVSALKALSTLYGTSYTHGPIATTIYPVSGSSIDWAYD-EGM 373

  Fly   370 KIHYTIELRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREI 413
            |..:..||||:|:.||:||...|   .:...|..:.:.|.|:.:
Frog   374 KYSFAFELRDEGQYGFLLPENQI---KKTCMETMLAVKAIAKSV 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	14/77 (18%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	105/300 (35%)
LOC105947369	XP_012818774.2	Propep_M14	33..104	CDD:366995	13/75 (17%)
LOC105947369	XP_012818774.2	Peptidase_M14_like	116..415	CDD:386095	107/313 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920