DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prat2 and Prat

DIOPT Version :9

Sequence 1:	NP_523949.2	Gene:	Prat2 / 38753	FlyBaseID:	FBgn0041194	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_001246972.1	Gene:	Prat / 40935	FlyBaseID:	FBgn0004901	Length:	546	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	419/502 - (83%)
Similarity:	459/502 - (91%)	Gaps:	3/502 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 EDATGMTCECGVFAAIACGDYPTQLDIAQMICLGLVALQHRGQESAGIVTSLGKSSKNFSVHKGM 113
            ::.||:|.|||||.||||||:|||:|||.:||||||||||||||||||.||.||.||||:|||||
  Fly    45 KELTGLTHECGVFGAIACGDWPTQMDIAHVICLGLVALQHRGQESAGIATSEGKCSKNFNVHKGM 109

  Fly   114 GMINNLFNDEAIRKLKGNLGIGHTRYSTAAASEVVNCQPFVVHTAHGALAIAHNGELVNCESLRR 178
            |||:.||||::::||:|||||||||||||..|.|||||||.|||.|||||:||||||||.|||||
  Fly   110 GMISTLFNDDSMKKLRGNLGIGHTRYSTAGGSGVVNCQPFEVHTTHGALALAHNGELVNNESLRR 174

  Fly   179 EVLERGVGLSTHSDSELIAQSLCCAPEDVSEHDGPNWPARIRHFMTLAPLSYSLVVMHKDKIYAV 243
            |||.|||||||||||||||||||||||||||.|||||||||||||.|||||||||:|.|||||||
  Fly   175 EVLARGVGLSTHSDSELIAQSLCCAPEDVSELDGPNWPARIRHFMMLAPLSYSLVIMLKDKIYAV 239

  Fly   244 RDSYGNRPLCLGKIVPVDAGHANINDQLAEGWVVSSESCGFLSIGARYVREVEPGEIIELSRNGY 308
            ||:|||||||:|||||::|||.|..|..|:|||||||||||||||||||||||||||:||||:||
  Fly   240 RDTYGNRPLCIGKIVPINAGHGNNLDTPADGWVVSSESCGFLSIGARYVREVEPGEIVELSRSGY 304

  Fly   309 RTVDIVERPDYKRMAFCIFEYVYFARSDSMFEGQMVYSARLQCGRQLARESPLDADLVSSVPESG 373
            ||||||||||:|||||||||||||||.||:|||||||:.||||||||.||:|::||:||||||||
  Fly   305 RTVDIVERPDFKRMAFCIFEYVYFARGDSIFEGQMVYTVRLQCGRQLWREAPVEADIVSSVPESG 369

  Fly   374 TAAAHGYARESGLPFGEVLCKNRYVGRTFIQPSTRLRQLGVAKKFGALAQNVEGKRIVLVDDSIV 438
            ||||||||||||:.|.||||:|||||||||||||||||||||||||||::||.|||:||:|||||
  Fly   370 TAAAHGYARESGIEFAEVLCRNRYVGRTFIQPSTRLRQLGVAKKFGALSENVAGKRLVLIDDSIV 434

  Fly   439 RGNTIGPIIKLLRDAGATEVHIRIASPPLQYPCYMGINIPTREELIANKLNADQLADHVGADSLA 503
            |||||||||||||||||.|||||||||||||||||||||||||||||||||.||||.||||||||
  Fly   435 RGNTIGPIIKLLRDAGAREVHIRIASPPLQYPCYMGINIPTREELIANKLNPDQLARHVGADSLA 499

  Fly   504 YLSVEGLVKAVQMNKAHVNPLKA---GYCTACLTGEYPGGLPEELSW 547
            ||||||||:|||:........|:   |:||||||||||||||:||||
  Fly   500 YLSVEGLVEAVQLKHRDAGDSKSKGTGHCTACLTGEYPGGLPDELSW 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prat2	NP_523949.2	PurF	57..544	CDD:223112	412/489 (84%)
		GPATase_N	58..340	CDD:238367	238/281 (85%)
		PRTases_typeI	351..487	CDD:206754	120/135 (89%)
Prat	NP_001246972.1	PurF	50..543	CDD:223112	413/492 (84%)
		GPATase_N	54..336	CDD:238367	238/281 (85%)
		PRTases_typeI	347..483	CDD:206754	120/135 (89%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471427
Domainoid	1	1.000	62	1.000	Domainoid score	I3745
eggNOG	1	0.900	-	-		E1_COG0034
Homologene	1	1.000	-	-		H68272
Inparanoid	1	1.050	337	1.000	Inparanoid score	I654
Isobase	1	0.950	-	0.591673	Normalized mean entropy	S1178
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257834at33208
OrthoFinder	1	1.000	-	-		FOG0002622
OrthoInspector	1	1.000	-	-		otm26540
orthoMCL	1	0.900	-	-		OOG6_101156
Panther	1	1.100	-	-	P	PTHR11907
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1034
SonicParanoid	1	1.000	-	-		X1724
	14	13.780