Protein Alignment vvl and pou2f2b

DIOPT Version :10

• Sequence 1: NP_001303384.1
• Gene: vvl / 38752
• FlyBaseID: FBgn0086680
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_009290402.2
• Gene: pou2f2b / 557055
• ZFINID: ZDB-GENE-060310-1
• Length: 710
• Species: Danio rerio
• Alignment Length: 691
• Identity: 199/691 - (28%)
• Similarity: 272/691 - (39%)
• Gaps: 216/691 - (31%)

  Fly    40 MQHHHHHHAAAAAAAHHQLPSSPSPN-GQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPA 103
            :|..|..|||....|..|.....:.. .|....|....:.....:.....|.|      .|.||.
Zfish   155 VQQSHVAHAANQQQAQQQAQQQANQQAAQQQSQGQSQSTQEQAAAAPVPPPPP------PHQLPL 213

  Fly   104 AAAVASAADTVKQEMSHLSQQTRIQQGMASPHAAWHAPHAGHYAPTGGSPLQY-----HHAMNGM 163
            :..:...|..::|.:       ::||.:..|         ||..|   ||.|:     .....|:
Zfish   214 SQPIQLTAQDIQQLL-------QLQQLVLVP---------GHTLP---SPAQFLLPQTQQGQQGL 259

  Fly   164 LHHPAHAVAAAHHQSVAPLHHTLRGE----SPQLHIHHHMGGGDRDAISGGEEDTPTS------- 217
            |..|          ::.||....:|.    .|:|.:.     ..|:.|:....:|.|:
Zfish   260 LSTP----------NLIPLPQQNQGSLLAAPPRLSLQ-----AQREKIAESSLNTVTTVTSHPEE 309

  Fly   218 ----DDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 278
                ::||.||:.||||||||||||.|||||:|.||||.||||||.|||||.|||||||||||||
Zfish   310 PSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLL 374

  Fly   279 QKWLEEA------------DSTTGSPTSIDKIA-----AQGRKRKKRTSIEVSVKGALEQHFHKQ 326
            :|||.:|            |||..||:|:...:     ..||:||||||||.:|:.|||..|...
Zfish   375 EKWLTDAAFFNVYSETMSMDSTLPSPSSLSSPSLGFEGLPGRRRKKRTSIETNVRVALEHSFLAN 439

  Fly   327 PKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTLGGDMMDGMPPGHMHHGGYHPHHD 391
            .||:::||..:::.|.:||||:|||||||||||||:.|.:        ..||
Zfish   440 QKPTSEEILLISEKLNMEKEVIRVWFCNRRQKEKRINPSS--------ATPP------------- 483

  Fly   392 MHGSPMGTHSHSHSPPMLSPQNMQSSAVAAHQLAAHXQSEIQESNSAAAASTPASLNSLSQQQQQ 456
            :...|..|   ||.||..||..|.|            |...|...|.:.|.|  :::|:
Zfish   484 LPSQPQPT---SHKPPCYSPHMMSS------------QGPRQTVGSLSTAVT--TMSSV------ 525

  Fly   457 QQQQQQQQHQQQQQHQQQQHTPNTPSSSAGSSATMTSQVMSPQSPLGSSSAGNQANNNNN----- 516
                                .|.|||   |.|.:.|...::| .|.|.||.....::..|
Zfish   526 --------------------CPMTPS---GPSLSSTPSPVTP-PPRGDSSPAPPTHSTLNLSTGS 566

  Fly   517 ----NNNNNNSSTNNNNNNNNNEEQVKH--HQQQQQQQQASSIAAAAAAAMYMDPMRYQHPHHPH 575
                |.:.:|..|:...:..|....|..  :|........::|.|.||:...: |:
Zfish   567 WHKKNGDVSNYITDFAASLRNTVRGVNTGLNQALLGSNPLATIQALAASGGQL-PI--------- 621

  Fly   576 PHPHQHPHLNPAHHPHLFHTSDQLQHSQQQTVGGT---------------SSNSQLSPGAGSNSG 625
                                 ..|:.|.:..:||:               ||...|:.|.|...|
Zfish   622 ---------------------SSLEGSSKVLIGGSGAQGAGLPSSLFLNHSSMLPLATGPGMGLG 665

  Fly   626 --------LPLQPPSSASPAGS-ASSVLGGHLNLNPLHQHH 657
                    .|:....|.||..| |||...|.:    ||..|
Zfish   666 GSAVGKTSFPVTGGMSPSPCSSPASSYSSGEM----LHSPH 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vvl	NP_001303384.1	POU	212..286	CDD:197673	56/96 (58%)
		Homeodomain	305..361	CDD:459649	33/55 (60%)
pou2f2b	XP_009290402.2	None