Protein Alignment vvl and HOXB7

DIOPT Version :9

• Sequence 1: NP_001303384.1
• Gene: vvl / 38752
• FlyBaseID: FBgn0086680
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 60/287 - (20%)
• Similarity: 93/287 - (32%)
• Gaps: 111/287 - (38%)

  Fly   102 PAAAAV-ASAADTVKQEMSHLSQQTRIQQGMASPHAAWHAPHAGHYAPTGGSPLQYHHAMNGMLH 165
            ||:::| |:.|...:...:..|...|...| |...|::.|...|.| |.||          ||..
Human    15 PASSSVFATGAFPEQTSCAFASNPQRPGYG-AGSGASFAASMQGLY-PGGG----------GMAG 67

  Fly   166 HPAHAVAAA--------HHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAISGGEEDTPTSDDLEA 222
            ..|..|.||        .:...||....|.|..|          ||....:|.:|
Human    68 QSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCP----------GDSAKAAGAKE---------- 112

  Fly   223 FAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEADS 287
                           |.|..|                   |.:.:|:        :..|:..:.:
Human   113 ---------------QRDSDL-------------------AAESNFR--------IYPWMRSSGT 135

  Fly   288 TTGSPTSIDKIAAQGRKRKKRT-----SIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEV 347
                          .|||.::|     ::|      ||:.||.....:.:....:|.:|.|.:..
Human   136 --------------DRKRGRQTYTRYQTLE------LEKEFHYNRYLTRRRRIEIAHTLCLTERQ 180

  Fly   348 VRVWFCNRR---QKEKRMTPPNTLGGD 371
            :::||.|||   :||.:...|.|.|.|
Human   181 IKIWFQNRRMKWKKENKTAGPGTTGQD 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vvl	NP_001303384.1	POU	212..286	CDD:197673	7/73 (10%)
		Homeobox	307..360	CDD:278475	15/60 (25%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		1/4 (25%)
		Homeobox	141..193	CDD:278475	14/57 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		6/14 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3844
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940