Protein Alignment vvl and POU5F2

DIOPT Version :10

• Sequence 1: NP_001303384.1
• Gene: vvl / 38752
• FlyBaseID: FBgn0086680
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_694948.1
• Gene: POU5F2 / 134187
• HGNCID: 26367
• Length: 328
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 102/294 - (34%)
• Similarity: 141/294 - (47%)
• Gaps: 59/294 - (20%)

  Fly   137 AWHAPHAGHYAPT----GGSP-------------LQYHHAMNGMLHHPAHAVAAAHHQSV----- 179
            |.|.| :.|:.|.    ||.|             |....|...::..||..........|
Human     2 AGHRP-SNHFCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPL 65

  Fly   180 APLHHTLRGE----SPQLHIHHHMGGGD------RDAISG-------------GEEDTPTSDDLE 221
            .||.|..||.    .|:|....   .||      ..|:.|             .|:.:....:|:
Human    66 GPLPHEFRGWIAPCRPRLGASE---AGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGILKELQ 127

  Fly   222 AFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLE--E 284
            ..||:.:|:|:.||::|||||:|:|.|:|.|.||||||||||.|||..||.||:|||:|||:  |
Human   128 QLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVE 192

  Fly   285 ADSTTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVR 349
            |::..|. ..::.|..|..| .:|.|.|..:..:||:.|.:.|||:.|:|:.:|..|||:|:|||
Human   193 AENLLGL-CKMEMILQQSGK-WRRASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVR 255

  Fly   350 VWFCNRRQKEKRMT----PPNTLG--GDMMDGMP 377
            |||.||.:...|.|    |...:|  |....|.|
Human   256 VWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAP 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vvl	NP_001303384.1	POU	212..286	CDD:197673	41/75 (55%)
		Homeodomain	305..361	CDD:459649	24/55 (44%)
POU5F2	NP_694948.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		8/23 (35%)
		Pou	121..192	CDD:459692	40/70 (57%)
		Homeodomain	<225..261	CDD:459649	19/35 (54%)