Protein Alignment vvl and Pou2f2

DIOPT Version :10

• Sequence 1: NP_001303384.1
• Gene: vvl / 38752
• FlyBaseID: FBgn0086680
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_038968890.1
• Gene: Pou2f2 / 117058
• RGDID: 621690
• Length: 825
• Species: Rattus norvegicus
• Alignment Length: 734
• Identity: 208/734 - (28%)
• Similarity: 274/734 - (37%)
• Gaps: 210/734 - (28%)

  Fly    48 AAAAAAAH-----HQLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHP-DPWMQTHHTHHLPAAAA 106
            |||||||.     ....||.|.....:|||             .|.| .|..|...|..|..:..
  Rat   159 AAAAAAASTSSSTSSASSSTSQTPASSGGG-------------DLPPSQPTSQPPGTPQLTLSQP 210

  Fly   107 VASAADTVKQEMS----------HLS--------QQTRIQQGMASPHAAWHAPHAGHYA-----P 148
            :...|..::|.:.          ||.        |..:.|.|:......:..|.....|     |
  Rat   211 IQLTAQDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQP 275

  Fly   149 TGGSPLQYHHAMNGMLHHPAHAVAAAHHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAISGGEED 213
            ..|.|.|.|..       |...:.:    :..|.....|...|..|:.|.......:..|..||.
  Rat   276 RAGLPTQLHPG-------PRSCIPS----TCPPYQAMTRPTLPDPHLSHPQPSKCLEPPSHPEEP 329

  Fly   214 TPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 278
            :.. ::||.||:.||||||||||||.|||||:|.||||.||||||.|||||.|||||||||||||
  Rat   330 SDL-EELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLL 393

  Fly   279 QKWLEEA-----DSTTGSPTSIDKIA-----AQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQE 333
            :|||.:|     ||:..||..:...:     ..||:||||||||.:|:.|||:.|....||:::|
  Rat   394 EKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEE 458

  Fly   334 ITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTLGGDMMDGMPPGHMHHGGYHPHHDMHGSPMG 398
            |..:|:.|.:||||:|||||||||||||:.|.:..                   |.....|.|.
  Rat   459 ILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAA-------------------PMLPSPGKPT- 503

  Fly   399 THSHSHSPPMLSPQNMQSSAVAAHQLAAHXQSEIQESNSAAAASTPA--------------SLNS 449
                |:||.:::||. .:..:...|.::. .:.:...:||.....|:              .|||
  Rat   504 ----SYSPHLVTPQG-GAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNS 563

  Fly   450 LSQQQQQQQQQQQQQHQQQQQHQQQQHTPNTPSSSAGSSATMTSQVMSPQ---SPLGSSSAGNQA 511
            :                              ||.:....||..|...|||   |.:|.:.....|
  Rat   564 I------------------------------PSVTPPPPATTNSTNPSPQGSHSAIGLTGLNPSA 598

  Fly   512 NNNNNNNNNNNSSTNNNNNNNNNEEQVKHHQQQQQQQQASSIAAAAAAAMYMDPMRYQHPHHPHP 576
            .:.....::..|.....||                     .:|....|...|.           |
  Rat   599 GSTMVGLSSGLSPALMGNN---------------------PLATIQGACCLMS-----------P 631

  Fly   577 HPHQH-PHLNPAHHPHLFHTSDQLQHSQQQTVGGTSSNSQLSPGAGSNSGLPLQP--PSSASPAG 638
            |.||. |.|                        |..:.|.|.|       .|..|  |.:|..|.
  Rat   632 HCHQSCPLL------------------------GLEAPSPLLP-------QPCHPALPLTALLAC 665

  Fly   639 SASSVLGGHLNLNPLHQHHHYQHHHHQQHHHHQQQQQQLHARRLFELSLQFGA-AAAPGAVRHFN 702
            |:.||.|..:.:..|......|........|   :.|.|......:|||.|.: |.|.|......
  Rat   666 SSPSVFGEGVRVLLLGSQWDRQEMGCSGRVH---RGQGLPGLMYLQLSLSFSSPALASGGTLPLT 727

  Fly   703 SFGGAG----GAGGEXHSS 717
            |...:|    ||.|. ..|
  Rat   728 SLDSSGNLVLGAAGAAPGS 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vvl	NP_001303384.1	POU	212..286	CDD:197673	55/78 (71%)
		Homeodomain	305..361	CDD:459649	34/55 (62%)
Pou2f2	XP_038968890.1	PRK10263	<231..>348	CDD:236669	30/128 (23%)
		POU	327..401	CDD:197673	55/74 (74%)
		Homeodomain	430..486	CDD:459649	34/55 (62%)
		POU2F1_C	<717..774	CDD:437368	9/30 (30%)