Protein Alignment vvl and POU6F2

DIOPT Version :9

• Sequence 1: NP_001303384.1
• Gene: vvl / 38752
• FlyBaseID: FBgn0086680
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_001357888.1
• Gene: POU6F2 / 11281
• HGNCID: 21694
• Length: 720
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 112/447 - (25%)
• Similarity: 161/447 - (36%)
• Gaps: 148/447 - (33%)

  Fly    41 QHHHHHHAAAAAAAHHQLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPAAA 105
            |.|..|       :|.|..:.|||..|.:..........|.|..|.|.|...:|..:......||
Human   278 QQHQPH-------SHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAA 335

  Fly   106 AVASAADTVKQEMSHLSQQTRIQ----------QG--------MASPHAAWHAPHAGHYAPTGG- 151
            |.|:|..::....:..:..:.:|          ||        |.:|     .|.:...:.|.|
Human   336 AAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNP-----GPSSQAASGTQGL 395

  Fly   152 -------------------------------------SPL----QYHH---------AMNGMLHH 166
                                                 ||:    |.|.         |..|.|.|
Human   396 QVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLH 460

  Fly   167 PAHAVAAAHHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAIS-----------GGEEDTPTSDDL 220
            .||:.|:   .|.:|:.......|         ......|:|           .||.|....:::
Human   461 LAHSQAS---MSQSPVRQASSSSS---------SSSSSSALSVGQLVSNPQTAAGEVDGVNLEEI 513

  Fly   221 EAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTIC-------------------------- 259
            ..|||.||.||:.||.||..||.||....|..:||:.||
Human   514 REFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTA 578

  Fly   260 ----------RFEALQLSFKNMCKLKPLLQKWLEEADS--TTGSPTSIDKIAAQ-GRKRKKRTSI 311
                      |||.|.::.|:..|:||:|::|:.||::  ..|.....:.|.:: .:|||:|||.
Human   579 KLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIGSEPSKKRKRRTSF 643

  Fly   312 EVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTL 368
            .......|..||.|...||.||:|.:|:.|..::|||||||||:||..|     ||:
Human   644 TPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALK-----NTI 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vvl	NP_001303384.1	POU	212..286	CDD:197673	32/109 (29%)
		Homeobox	307..360	CDD:278475	25/52 (48%)
POU6F2	NP_001357888.1	Pou	506..615	CDD:389985	32/108 (30%)
		Homeobox	639..693	CDD:365835	26/58 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810