Protein Alignment vvl and pou2f2

DIOPT Version :10

• Sequence 1: NP_001303384.1
• Gene: vvl / 38752
• FlyBaseID: FBgn0086680
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_002936445.2
• Gene: pou2f2 / 100497329
• XenbaseID: XB-GENE-876751
• Length: 658
• Species: Xenopus tropicalis
• Alignment Length: 757
• Identity: 212/757 - (28%)
• Similarity: 278/757 - (36%)
• Gaps: 266/757 - (35%)

  Fly    21 GGYHT---SSPRSAADAGEMKYMQHHH-----------HHHAAAAAAAHH--------------- 56
            |..||   .||.|.|.|.|::..:..|           .:....|.:.|.
 Frog    15 GSEHTWPFKSPLSLAGADEIRMSKPGHLSKLHTEGGVTDNERNGADSLHEVQQNKGSPFSLSPKI 79

  Fly    57 ----------QLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPAAAAVASAA 111
                      .|||:|.|.         :.|.............|......|..|.|.:.:|...
 Frog    80 TDEESGDRSPSLPSTPVPQ---------MPSAPPTPQAPPAPQQPPTSLPQTQLLLAGSQLAGLT 135

  Fly   112 DTVKQEMSHLSQQTR-----IQQGMASPHAAWHAPHAGHYAPTGGSPLQYHHAMNGMLHHPAHAV 171
            ..:..:...|.||.:     :||.    .||..|..:|..:.|..:..|..|.:  .|..|.|..
 Frog   136 ALLPAQQQLLLQQAQLLAAAVQQS----SAAASATQSGSDSQTLPTSQQQPHQL--ALSQPIHLT 194

  Fly   172 AAAHHQSVA----------PLHHTLRGESPQLHIHHHMGGGDRDAISG----------------- 209
            |....|.:.          ||..|.:...||      .|.|.:..||.
 Frog   195 AQDIQQLLQLQQLVLVPGHPLQSTPQFLLPQ------AGQGQQGLISAPNLFQLPQQNQGNLLSG 253

  Fly   210 --------------GEEDTP-------TS--------DDLEAFAKQFKQRRIKLGFTQADVGLAL 245
                          |.:|||       ||        ::||.||:.||||||||||||.|||||:
 Frog   254 QPRPSLPTQAVSRPGSQDTPLLSHSDQTSHPEEPNDLEELEQFARTFKQRRIKLGFTQGDVGLAM 318

  Fly   246 GTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEA-----DSTTGSPTSIDKIAA----- 300
            |.||||.||||||.|||||.|||||||||||||||||.:|     |||..||..:.....
 Frog   319 GKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLSDAETMSVDSTLPSPNPLSSPGGGYEGL 383

  Fly   301 QGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPP 365
            .||:||||||||.:|:.|||:.|....||:::||..:|:.|::||||:|||||||||||||:.|.
 Frog   384 PGRRRKKRTSIETNVRYALEKSFIANQKPTSEEILVIAEQLKMEKEVIRVWFCNRRQKEKRINPC 448

  Fly   366 NTLGGDMMDGMPPGHMHHGGYHPHHDMHGSPMGTHSHSHSPPMLSPQNMQSSAVAAHQLAAHXQS 430
            ::.......|                 .||..|.|             :.||.|:|..|.:. .|
 Frog   449 SSTPLTPTQG-----------------KGSLFGAH-------------LVSSPVSAPILTSQASS 483

  Fly   431 EIQESNSAAAASTPASLNSLSQQQQQQQQQQQQQHQQQQQHQQQQHTPNTPSSSAGSSATMTSQV 495
            .:    |....:.|.::.||:.                         |..||::|..|||
 Frog   484 NL----STTVTTLPCAVGSLAH-------------------------PRPPSNTAPPSAT----- 514

  Fly   496 MSPQSPLGSSSAGNQANNNNNNNNNNNSSTNNNNNNNNNEEQVKHHQQQQQQQQASSIAAAAAAA 560
               ..|..|:||..|            |||::.                   ...:.::.:|.|.
 Frog   515 ---PPPSNSTSASPQ------------SSTHSG-------------------LSLTGLSPSAGAT 545

  Fly   561 MYMDPMRYQHPHHPHPHPHQHPHLNPAHHPHLFHTSDQLQHSQQQTVGGT-------SSNSQLSP 618
            |.                .....|||.     ....:.|...|..|.||:       .|...|..
 Frog   546 ML----------------GVSAGLNPT-----LMAGNPLATIQALTSGGSLPLSGLDCSGGLLLA 589

  Fly   619 GAGSNSGLPLQPPSSASPAG----SAS----SVLGGHLNLNP 652
            |..|..|| :.||...:|.|    |:|    |..||..:|:|
 Frog   590 GGSSTPGL-VSPPLFLNPGGLPLISSSLARISSAGGTPSLSP 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vvl	NP_001303384.1	POU	212..286	CDD:197673	60/93 (65%)
		Homeodomain	305..361	CDD:459649	34/55 (62%)
pou2f2	XP_002936445.2	POU	285..359	CDD:197673	54/73 (74%)
		Homeodomain	388..444	CDD:459649	34/55 (62%)
		POU2F1_C	<548..624	CDD:437368	21/81 (26%)