Protein Alignment Rsph3 and Rsph3a

DIOPT Version :9

• Sequence 1: NP_648059.1
• Gene: Rsph3 / 38751
• FlyBaseID: FBgn0052392
• Length: 659
• Species: Drosophila melanogaster
• Sequence 2: NP_080065.4
• Gene: Rsph3a / 66832
• MGIID: 1914082
• Length: 516
• Species: Mus musculus
• Alignment Length: 577
• Identity: 174/577 - (30%)
• Similarity: 264/577 - (45%)
• Gaps: 114/577 - (19%)

  Fly   119 RPI----RREAGIADNRDNHV-------GNPPQRSHFSRSNQEVRSFADELSQKLRFLAPEEQNY 172
            ||:    ||.|| ...|:..|       |||..|:                  .|.||.|
Mouse    15 RPLHQRARRPAG-GRGREPEVPFTTDPSGNPAGRN------------------CLEFLPP----- 55

  Fly   173 GGRQ--SANSGAWMDPAMSQRPRFETTVPQGIFLPPP-HEVQMIPATMLRRHVYAYSSYPMILQG 234
            ||..  ||..|....| ::.||......|.|...|.| |.:|:..        |..|..|...:.
Mouse    56 GGTSGCSATDGGATVP-LALRPFLRERRPLGSQHPCPWHYLQVSD--------YDDSLAPTCFRA 111

  Fly   235 YLTKETGSESKEQKVTATRLNGLRATAAVAAATAAASKSSRNDTQSLAGGLHITKAQFQQQLQQR 299
            :|.:...|.:..|                     |::.:..|...:.|.||:...::.:....||
Mouse   112 HLHRRGSSSTLNQ---------------------ASAMTDPNPRTAEASGLYTYSSRPRAVACQR 155

  Fly   300 RSTSNNNNNSSSNISDKRPVVPPPEPYKNVMYDRRVIKGSNFG--NASLVTDVDPFD--KAAELR 360
            |...:         |..:| |..|..|.|:|||||||:|:.:.  ...:....||.:  :..:.|
Mouse   156 RRHRD---------SILQP-VEEPMSYGNIMYDRRVIRGNTYALPTGQVPGQPDPLELQRQQQAR 210

  Fly   361 RRNMLRKRTMQCRNQRNVLGTPPPVKGRKHETIQTEKYLEKLVQRPPEFTIDTQTDLFLEKPPTP 425
            ||.:.|||..:....|    ||.||:||||..||||.|||::..|..|..::.|||.||::||||
Mouse   211 RRALARKRAQEQLKPR----TPEPVEGRKHVDIQTELYLEEIADRIVEVDMECQTDAFLDRPPTP 271

  Fly   426 PFIPAKVGVDVATEIGEGELFHFDAEAQPIIDVLVDACIEQSMLEVAHEMELSSLRRKQEEFLAQ 490
            .|||||.|.||||:|..||||.||.|.:|:::|||...||||:|||..|.||::||.:|..:...
Mouse   272 LFIPAKTGKDVATQILGGELFDFDLEVKPMLEVLVGKTIEQSLLEVMEEEELANLRARQYAYEEI 336

  Fly   491 REAELAELRRLEAEELRLQAEKERRLRQD-AIAKELDAEMQKSVTAAKLLQGHIASLVPEVLENI 554
            |..||||::|||.:|.|.:.|||||.:|. .|..:.:..:|| ::|....:.::|:|:|.|.:.:
Mouse   337 RNVELAEVQRLEEQERRHREEKERRKKQQWEIVHKRNETLQK-ISALIFARQYLANLLPSVFDKL 400

  Fly   555 EPAS---DAVKKEQLMKSVCPWLSAEVAEEVGHIVDSREILTAIIQEIIKQRAEIYAGYKEPESE 616
            ..:.   |.:::: :.....|||..||.:.:.|.:..|.:|..:|::::::|..   .|:..|:.
Mouse   401 RNSGFFYDPIERD-IEVGFLPWLMNEVEKSMEHSMVGRTVLDMLIRDVVERRIN---DYEHKEAM 461

  Fly   617 PSG--------------PDAGVCEEEGCAIDEMEACPCESETEMEECPEPPPPAPHL 659
            |.|              |.......:...:|.:.:.|..|:..     :|.....||
Mouse   462 PPGQKTNVINGPNTVTDPSVTTLHTQKPVLDRVSSQPAPSQER-----KPVEEGGHL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rsph3	NP_648059.1	Radial_spoke_3	326..604	CDD:283702	114/285 (40%)
Rsph3a	NP_080065.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		10/30 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..139		3/39 (8%)
		Radial_spoke_3	172..451	CDD:283702	114/284 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..233		13/46 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	459..516		10/60 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850809
Domainoid	1	1.000	196	1.000	Domainoid score	I3123
eggNOG	1	0.900	-	-		E1_2CMM4
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H12043
Inparanoid	1	1.050	203	1.000	Inparanoid score	I3739
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D406327at33208
OrthoFinder	1	1.000	-	-		FOG0006135
OrthoInspector	1	1.000	-	-		otm43988
orthoMCL	1	0.900	-	-		OOG6_104764
Panther	1	1.100	-	-	LDO	PTHR21648
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10534
SonicParanoid	1	1.000	-	-		X5066
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790